Metabolic regulation of the hallmarks of stem cell biology Review
| Authors: | Jackson, B. T.; Finley, L. W. S. |
| Review Title: | Metabolic regulation of the hallmarks of stem cell biology |
| Abstract: | Stem cells perform many different functions, each of which requires specific metabolic adaptations. Over the past decades, studies of pluripotent and tissue stem cells have uncovered a range of metabolic preferences and strategies that correlate with or exert control over specific cell states. This review aims to describe the common themes that emerge from the study of stem cell metabolism: (1) metabolic pathways supporting stem cell proliferation, (2) metabolic pathways maintaining stem cell quiescence, (3) metabolic control of cellular stress responses and cell death, (4) metabolic regulation of stem cell identity, and (5) metabolic requirements of the stem cell niche. © 2024 Elsevier Inc. |
| Keywords: | aged; review; nonhuman; cell proliferation; cytology; cell death; cell division; cell differentiation; physiology; stem cell; stem cells; cellular stress response; stem cell niche; cell metabolism; metabolic regulation; human; male; female |
| Journal Title: | Cell Stem Cell |
| Volume: | 31 |
| Issue: | 2 |
| ISSN: | 1934-5909 |
| Publisher: | Cell Press |
| Date Published: | 2024-02-01 |
| Start Page: | 161 |
| End Page: | 180 |
| Language: | English |
| DOI: | 10.1016/j.stem.2024.01.003 |
| PUBMED: | 38306993 |
| PROVIDER: | scopus |
| PMCID: | PMC10842269 |
| DOI/URL: | |
| Notes: | Review -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK corresponding author is Lydia Finley -- Source: Scopus |
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