Psychometric properties of the functional assessment of cancer therapy-general for evaluating quality of life in patients with life-limiting illness in the emergency department Journal Article


Authors: Yusufov, M.; Adeyemi, O.; Flannery, M.; Bouillon-Minois, J. B.; Van Allen, K.; Cuthel, A. M.; Goldfeld, K. S.; Ouchi, K.; Grudzen, C. R.
Article Title: Psychometric properties of the functional assessment of cancer therapy-general for evaluating quality of life in patients with life-limiting illness in the emergency department
Abstract: Background: The Functional Assessment of Cancer Therapy-General (FACT-G) is a widely used quality-of-life measure. However, no studies have examined the FACT-G among patients with life-limiting illnesses who present to emergency departments (EDs). Objective: The goal of this study was to examine the psychometric properties of the FACT-G among patients with life-limiting illnesses who present to EDs in the United States. Methods: This cross-sectional study pooled data from 12 EDs between April 2018 and January 2020 (n = 453). Patients enrolled in the study were adults with one or more of the four life-limiting illnesses: advanced cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, or End-Stage Renal Disease. We conducted item, exploratory, and confirmatory analyses (exploratory factor analysis [EFA] and confirmatory factor analysis [CFA]) to determine the psychometric properties of the FACT-G. Results: The FACT-G had good internal consistency (Cronbach's alpha α = 0.88). The simplest EFA model was a six-factor structure. The CFA supported the six-factor structure, evidenced by the adequate fit indices (comparative fit index = 0.93, Tucker–Lewis index = 0.92, root-mean-square error of approximation = 0.05; 90% confidence interval: 0.04 – 0.06). The six-factor structure comprised the physical, emotional, work and daily activities-related functional well-being, and the family and friends-related social well-being domains. Conclusions: The FACT-G is a reliable measure of health-related quality of life among patients with life-limiting illnesses who present to the ED. Clinical Trial Registration: NCT03325985.
Keywords: functional assessment; neoplasm staging; quality of life; confidence intervals; heart failure; physical activity; employment status; activities of daily living; pulmonary disease, chronic obstructive; descriptive statistics; funding source; kidney failure, chronic; interpersonal relations; exploratory research; instrument validation; clinical assessment tools; coefficient alpha; terminally ill patients; cross sectional studies; oncologic care; human; reliability and validity; emergency service; psychological well-being; item analysis; psychometrics -- evaluation
Journal Title: Journal of Palliative Medicine
Volume: 27
Issue: 1
ISSN: 1096-6218
Publisher: Mary Ann Liebert, Inc  
Date Published: 2024-01-01
Start Page: 63
End Page: 74
Language: English
DOI: 10.1089/jpm.2022.0270
PROVIDER: EBSCOhost
PROVIDER: cinahl
PUBMED: 37672598
PMCID: PMC11074445
DOI/URL:
Notes: PDF incorrectly associates the affiliation "Ronald O. Perelman Center for Emergency Services" with MSK when it should be NYU Langone -- Source: Cinahl
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  1. Corita Reilley Grudzen
    31 Grudzen