Unbalanced regularized optimal mass transport with applications to fluid flows in the brain Journal Article


Authors: Chen, X.; Benveniste, H.; Tannenbaum, A. R.
Article Title: Unbalanced regularized optimal mass transport with applications to fluid flows in the brain
Abstract: As a generalization of the optimal mass transport (OMT) approach of Benamou and Brenier’s, the regularized optimal mass transport (rOMT) formulates a transport problem from an initial mass configuration to another with the optimality defined by the total kinetic energy, but subject to an advection-diffusion constraint equation. Both rOMT and the Benamou and Brenier’s formulation require the total initial and final masses to be equal; mass is preserved during the entire transport process. However, for many applications, e.g., in dynamic image tracking, this constraint is rarely if ever satisfied. Therefore, we propose to employ an unbalanced version of rOMT to remove this constraint together with a detailed numerical solution procedure and applications to analyzing fluid flows in the brain. © 2024, The Author(s).
Keywords: diffusion; kinetics; brain; biological transport; pharmacokinetics; fluid flow; transport at the cellular level; article; advection
Journal Title: Scientific Reports
Volume: 14
ISSN: 2045-2322
Publisher: Nature Publishing Group  
Date Published: 2024-01-01
Start Page: 1111
Language: English
DOI: 10.1038/s41598-023-50874-y
PUBMED: 38212659
PROVIDER: scopus
PMCID: PMC10784574
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Xinan Chen
    5 Chen