Elevated brain natriuretic peptide in a patient with metastatic cancer without heart failure: A case study Journal Article


Authors: Chen, L. L.; Dulu, A. O.; Pastores, S. M.
Article Title: Elevated brain natriuretic peptide in a patient with metastatic cancer without heart failure: A case study
Abstract: Brain natriuretic peptide (BNP) is a well-established biomarker for heart failure (HF). However, its diagnostic utility can be limited in patients with comorbidities that independently elevate serum BNP levels, including chronic renal failure and sepsis. We describe a rare occurrence of significantly elevated serum BNP levels in a patient with metastatic urothelial cancer without HF or obvious signs of sepsis. The report highlights the need for considering alternative causes for increased serum BNP levels, especially in the presence of malignancy. © 2024 Lippincott Williams and Wilkins. All rights reserved.
Keywords: neoplasm; neoplasms; biomarkers; biological marker; heart failure; sepsis; brain natriuretic peptide; critical care; metastatic cancer; natriuretic peptide, brain; humans; human
Journal Title: Journal of the American Association of Nurse Practitioners
Volume: 36
Issue: 1
ISSN: 2327-6886
Publisher: American Association of Nurse Practitioners  
Date Published: 2024-01-01
Start Page: 73
End Page: 76
Language: English
DOI: 10.1097/jxx.0000000000000927
PUBMED: 37471564
PROVIDER: scopus
DOI/URL:
Notes: Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK corresponding author is Leon Chen -- Source: Scopus
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MSK Authors
  1. Stephen Pastores
    252 Pastores
  2. Alina Oana Dulu
    17 Dulu
  3. Leon Lin Chen
    52 Chen