Advances in MRI-based assessment of rectal cancer post-neoadjuvant therapy: A comprehensive review Review


Authors: Miranda, J.; Causa Andrieu, P.; Nincevic, J.; Gomes de Farias, L. D. P.; Khasawneh, H.; Arita, Y.; Stanietzky, N.; Fernandes, M. C.; De Castria, T. B.; Horvat, N.
Review Title: Advances in MRI-based assessment of rectal cancer post-neoadjuvant therapy: A comprehensive review
Abstract: Rectal cancer presents significant diagnostic and therapeutic challenges, with neoadjuvant therapy playing a pivotal role in improving resectability and patient outcomes. MRI serves as a critical tool in assessing treatment response. However, differentiating viable tumor tissue from therapy-induced changes on MRI remains a complex task. In this comprehensive review, we explore treatment options for rectal cancer based on resectability status, focusing on the role of MRI in guiding therapeutic decisions. We delve into the nuances of MRI-based evaluation of treatment response following neoadjuvant therapy, paying particular attention to emerging techniques like radiomics. Drawing from our insights based on the literature, we provide essential recommendations for post-neoadjuvant therapy management of rectal cancer, all within the context of MRI-based findings. © 2023 by the authors.
Keywords: treatment response; neoadjuvant therapy; magnetic resonance imaging; rectal cancer
Journal Title: Journal of Clinical Medicine
Volume: 13
Issue: 1
ISSN: 2077-0383
Publisher: MDPI  
Date Published: 2024-01-01
Start Page: 172
Language: English
DOI: 10.3390/jcm13010172
PROVIDER: scopus
PMCID: PMC10780006
PUBMED: 38202179
DOI/URL:
Notes: Review -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK Corresponding author is Joao Miranda -- Source: Scopus
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