Association between copayment assistance, insurance type, prior authorization, and time to receipt of oral anticancer drugs Journal Article


Authors: Lichtenstein, M. R. L.; Beauchemin, M. P.; Raghunathan, R.; Lee, S.; Doshi, S. D.; Law, C.; Accordino, M. K.; Elkin, E. B.; Wright, J. D.; Hershman, D. L.
Article Title: Association between copayment assistance, insurance type, prior authorization, and time to receipt of oral anticancer drugs
Abstract: PURPOSE: Oral anticancer drugs (OACDs) have become increasingly prevalent over the past decade. OACD prescriptions require coordination between payers and providers, which can delay drug receipt. We examined the association between insurance type, pursuit of copayment assistance, pursuit of prior authorization (PA), and time to receipt (TTR) for new OACD prescriptions. METHODS: We prospectively collected data on new OACD prescriptions for adult oncology patients from January 1, 2018, to December 31, 2019, including demographic and clinical characteristics, insurance type, and pursuit of PA and copayment assistance. TTR was defined as the number of days from prescription to OACD receipt. We summarized TTR using cumulative incidence and compared TTR by insurance type, pursuit of copayment assistance, and PA activity using the log-rank test. RESULTS: Our cohort of 1,024 patients was 53% male, and 40% were younger than 65. Twenty-six percent had commercial insurance only, 16% had Medicaid only, and 59% had Medicare with or without additional insurance. Eighty-six percent of prescriptions were successfully received. Across all prescriptions, 69% involved PA activity, and 21% involved the copayment assistance process. In unadjusted analyses, prescriptions involving the copayment assistance process had longer TTR compared with those not involving assistance (log-rank P value = .005) and OACDs covered by Medicare/commercial insurance had a longer TTR compared with Medicaid (log-rank P value = .006). The PA process was not associated with TTR (log-rank P value = .124). CONCLUSION: The process for obtaining OACDs is complex. The copayment assistance process and Medicare/commercial insurance are associated with delayed TTR. New policies are needed to reduce time to OACD receipt.
Keywords: adult; aged; antineoplastic agents; united states; antineoplastic agent; neoplasm; neoplasms; medicaid; medicare; humans; human; male; female; prior authorization
Journal Title: JCO Oncology Practice
Volume: 20
Issue: 1
ISSN: 2688-1527
Publisher: American Society of Clinical Oncology  
Date Published: 2024-01-01
Start Page: 85
End Page: 92
Language: English
DOI: 10.1200/op.23.00205
PUBMED: 38033273
PROVIDER: scopus
PMCID: PMC10827292
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Sahil Deepak Doshi
    18 Doshi