Symptomatic necrosis with antibody-drug conjugates and concurrent stereotactic radiotherapy for brain metastases Research Letter

   

Authors:	Lebow, E. S.; Pike, L. R. G.; Seidman, A. D.; Moss, N.; Beal, K.; Yu, Y.
Title:	Symptomatic necrosis with antibody-drug conjugates and concurrent stereotactic radiotherapy for brain metastases
Abstract:	This cohort study investigates whether brain metastases that manifest after stereotactic radiotherapy with concurrent antibody-drug conjugates are associated with an increased risk of symptomatic radiation necrosis.
Keywords:	adult; aged; prospective studies; confidence intervals; neoplasm metastasis; data analysis software; tumor necrosis factor; regression; descriptive statistics; funding source; middle age; retrospective design; antineoplastic agents, combined -- therapeutic use; antibodies, monoclonal -- therapeutic use; brain neoplasms -- radiotherapy; record review; human; male; female; radiosurgery -- methods
Journal Title:	JAMA Oncology
Volume:	9
Issue:	12
ISSN:	2374-2437
Publisher:	American Medical Association
Date Published:	2023-12-01
Start Page:	1729
End Page:	1733
Language:	English
DOI:	10.1001/jamaoncol.2023.4492
PROVIDER:	EBSCOhost
PROVIDER:	cinahl
PMCID:	PMC10603573
PUBMED:	37883079
DOI/URL:	https://search.ebscohost.com/login.aspx?direct=true&AuthType=ip,shib&db=cin20&AN=174421562&site=ehost-live&scope=site&custid=s2915669
Notes:	Accession Number: 174421562 -- Entry Date: 20231228 -- Revision Date: 20231229 -- Publication Type: Journal Article; letter; research; tables/charts -- Journal Subset: Peer Reviewed; USA -- Special Interest: Oncologic Care -- Grant Information: Caris Life Sciences and Delfi Diagnostics Inc.,. -- Source: Cinahl

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