A quality improvement initiative standardizing premedication for blood product transfusions Journal Article
| Authors: | Shahid, S.; Rosenzweig, J.; Troullioud Lucas, A.; McThenia, S. S.; Fong, C.; Degliuomini, M. D.; Wuest, D.; Kaicker, S.; Slotkin, E. K. |
| Article Title: | A quality improvement initiative standardizing premedication for blood product transfusions |
| Abstract: | For children with cancer, blood product transfusions are crucial, but can be complicated by transfusion reactions. To prevent these complications, premedication is often given, although not always evidence-based. Herein, we describe a significant decrease in the use of premedication (72%–28%) at our institution after the implementation of standardized guidelines, without an increase in transfusion reactions (3.2% prior vs. 1.5% after standardization). Importantly, there were no severe transfusion reactions leading to hospitalization or death. Our results provide evidence in favor of more judicious use of premedication prior to transfusions in patients 21 years and younger being treated for cancer. © 2023 Wiley Periodicals LLC. |
| Keywords: | adult; child; controlled study; major clinical study; neoplasm; neoplasms; thrombocyte; practice guideline; retrospective study; childhood cancer; standardization; hypotension; hospitalization; blood transfusion reaction; total quality management; paracetamol; blood transfusion; erythrocyte; pediatric oncology; thrombocyte transfusion; quality improvement; diphenhydramine; premedication; transfusion; platelets; humans; human; female; article; red blood cells; transfusion reaction; blood product |
| Journal Title: | Pediatric Blood and Cancer |
| Volume: | 71 |
| Issue: | 1 |
| ISSN: | 1545-5009 |
| Publisher: | Wiley Periodicals, Inc |
| Date Published: | 2024-01-01 |
| Start Page: | e30753 |
| Language: | English |
| DOI: | 10.1002/pbc.30753 |
| PUBMED: | 37899699 |
| PROVIDER: | scopus |
| PMCID: | PMC10872576 |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Sanam Shahid -- Source: Scopus |
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