American Society of Transplantation and Cellular Therapy Series: #7 - Management of respiratory syncytial virus infections in hematopoietic cell transplant recipients Guidelines


Authors: El Chaer, F.; Kaul, D. R.; Englund, J. A.; Boeckh, M.; Batista, M. V.; Seo, S. K.; Carpenter, P. A.; Navarro, D.; Hirsch, H. H.; Ison, M. G.; Papanicolaou, G. A.; Chemaly, R. F.
Title: American Society of Transplantation and Cellular Therapy Series: #7 - Management of respiratory syncytial virus infections in hematopoietic cell transplant recipients
Abstract: The Practice Guidelines Committee of the American Society of Transplantation and Cellular Therapy (ASTCT) partnered with its Transplant Infectious Disease Special Interest Group (TID-SIG) to update the 2009 compendium-style infectious disease guidelines for hematopoietic cell transplantation (HCT). A new approach was adopted to better serve clinical providers by publishing each standalone topic in the infectious disease series in a concise format of frequently asked questions (FAQ), tables, and figures. Experts in HCT and infectious diseases identified FAQs and then provided answers based on the strength of the recommendation and the level of supporting evidence. In the seventh guideline in the series, we focus on the respiratory syncytial virus (RSV) with FAQs addressing epidemiology, clinical diagnosis, prophylaxis, and treatment. Special consideration was given to RSV in pediatric, cord blood, haploidentical, and T cell-depleted HCT and chimeric antigen receptor T cell therapy recipients, as well as to identify future research directions. © 2023 The American Society for Transplantation and Cellular Therapy
Keywords: child; drug efficacy; nonhuman; united states; staging; diagnostic procedure; incidence; immunoglobulin; practice guideline; hematopoietic stem cell transplantation; risk factor; monoclonal antibody; vaccination; medical society; umbilical cord blood; infection prevention; t cell depletion; guidelines; infection control; palivizumab; ribavirin; graft recipient; viral upper respiratory tract infection; respiratory syncytial virus infections; hematologic disease; communicable disease; seasonal variation; hematopoietic cell transplantation; communicable diseases; kidney dysfunction; clinical outcome; respiratory syncytial virus; transplant recipients; aerosol; hyperimmune globulin; lower respiratory tract infection; humans; prognosis; human; article; haploidentical transplantation; human respiratory syncytial virus; chimeric antigen receptor t-cell immunotherapy; respiratory syncytial virus infection; respiratory syncytial virus, human; respiratory syncytial virus vaccine
Journal Title: Transplantation and Cellular Therapy
Volume: 29
Issue: 12
ISSN: 2666-6375
Publisher: Elsevier Inc.  
Date Published: 2023-12-01
Start Page: 730
End Page: 738
Language: English
DOI: 10.1016/j.jtct.2023.09.018
PUBMED: 37783338
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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  1. Susan Seo
    120 Seo