APOBEC3 as a driver of genetic intratumor heterogeneity Journal Article
| Authors: | Venkatesan, S.; Angelova, M.; Bartkova, J.; Bakhoum, S. F.; Bartek, J.; Kanu, N.; Swanton, C. |
| Article Title: | APOBEC3 as a driver of genetic intratumor heterogeneity |
| Abstract: | Our recent study revealed that APOBEC3B is upregulated during the preinvasive stages of non-small cell lung cancer and breast cancer. In addition to its role in mediating single nucleotide variants, we propose that APOBEC3 promotes copy number intratumor heterogeneity prior to invasion, providing a substrate for cancer evolution. © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC. |
| Keywords: | breast cancer; chromosomal instability; non-small cell lung cancer; intratumor heterogeneity; apobec |
| Journal Title: | Molecular and Cellular Oncology |
| Volume: | 10 |
| ISSN: | 2372-3556 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2023-01-01 |
| Start Page: | 2014734 |
| Language: | English |
| DOI: | 10.1080/23723556.2021.2014734 |
| PROVIDER: | scopus |
| PMCID: | PMC10730158 |
| PUBMED: | 38116246 |
| DOI/URL: | |
| Notes: | Source: Scopus |
