Understanding breast cancer oncology: The need for mastectomy and axillary staging Book Section
| Authors: | Pawloski, K. R.; Tadros, A. B. |
| Editors: | Vidya, R.; Becker, H. |
| Article/Chapter Title: | Understanding breast cancer oncology: The need for mastectomy and axillary staging |
| Abstract: | The treatment of breast cancer has evolved from the Halstedian era to the modern approach defined by surgical de-escalation in a multidisciplinary setting. Prospective trials have demonstrated survival equivalence between mastectomy and lumpectomy with radiation. While breast-conserving surgery is oncologically safe for patients with early-stage disease, mastectomy remains the gold standard operation in cases of extensive multicentric breast cancer, inflammatory breast cancer, and risk-reduction for BRCA1 and BRCA2 mutation carriers. The type of mastectomy (total, skin sparing, or nipple sparing) performed depends upon patient and tumor factors, as well as the desire for breast reconstruction, for which preservation of the skin envelope is required. Post-mastectomy radiation therapy is indicated for patients at high risk of locoregional recurrence based on tumor size, margins, and nodal status. Sentinel lymph node biopsy is routinely performed for clinically node-negative patients with invasive breast cancer and may be offered to node-positive patients who successfully downstage following neoadjuvant chemotherapy. Complete axillary clearance remains indicated in the setting of high nodal burden or failure to achieve a complete axillary response to systemic therapy. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023. |
| Book Title: | Prepectoral Breast Reconstruction: Current Trends and Techniques |
| ISBN: | 978-3-031-15589-5 |
| Publisher: | Springer Nature |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2023-01-01 |
| Start Page: | 23 |
| End Page: | 37 |
| Language: | English |
| DOI: | 10.1007/978-3-031-15590-1_3 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 3 -- Source: Scopus |
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