Zolpidem in elderly patients with acute treatment resistant catatonia: A case report Journal Article


Authors: Wendt, L.; Hornung, M.; Sami, R.
Article Title: Zolpidem in elderly patients with acute treatment resistant catatonia: A case report
Abstract: Catatonia is defined by the Diagnostic and Statistical Manual of Mental Disorders-fifth Edition (DSM-5) as the presence of 3 or more of the following symptoms: catalepsy, waxy flexibility, stupor, agitation, mutism, negativism, posturing, mannerisms, stereotypies, grimacing, echolalia, and echopraxia. Screening instruments, such as the Bush Francis Catatonia Rating Scale (BFCRS) or the Northoff Catatonia Scale, are utilized to screen and track the severity and course of symptoms. The primary pharmacologic treatment for catatonia is the lorazepam challenge test. Second-line pharmacologic therapies are indicated when patients have an insufficient response to benzodiazepines and electroconvulsive therapy (ECT). In this case report, we report a case of a geriatric patient given high-dose zolpidem as an alternative agent with cardiac contraindications to ECT. © The Author(s) 2023.
Keywords: clinical article; aged; range of motion; case report; drug dose reduction; treatment duration; drug megadose; follow up; lorazepam; clinical assessment; coronary artery bypass graft; acetylsalicylic acid; comorbidity; major depression; metoprolol; daily life activity; hospital admission; hospital discharge; occupational therapy; alternative medicine; weakness; drug dose increase; treatment contraindication; atorvastatin; coronary artery disease; geriatric patient; outpatient care; cerebrovascular accident; acute disease; geriatrics; nursing home; duloxetine; suicidal ideation; medical history; internal validity; falling; zolpidem; tamsulosin; mutism; psychiatric; liaison psychiatry; refractory disease; brain artery aneurysm; human; male; article; defense mechanism; immobility; electroconvulsive therapy; psychotherapeutics; abnormal posture; behavior disorder assessment; bush francis catatonia rating scale score; catatonia; multiinfarct dementia; staring spell; treatment resistant depression
Journal Title: Hospital Pharmacy
Volume: 58
Issue: 5
ISSN: 0018-5787
Publisher: Sage Publications  
Date Published: 2023-10-01
Start Page: 444
End Page: 447
Language: English
DOI: 10.1177/00185787231161514
PROVIDER: scopus
PMCID: PMC10498965
PUBMED: 37711409
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Lisa Marie Wendt
    1 Wendt