Intraductal neoplasms of the pancreatobiliary tract: Navigating the alphabet Review

  


Authors: Xue, Y.; Basturk, O.
Review Title: Intraductal neoplasms of the pancreatobiliary tract: Navigating the alphabet
Abstract: Cancers of the pancreatobiliary tract are diseases with unfavourable prognoses. In the last couple of decades, two types of lesions have been described as precursors that precede pancreatobiliary cancers. These include incidental microscopic (flat) lesions known as pancreatic intra-epithelial neoplasia and biliary intra-epithelial neoplasia, and grossly visible, mass-forming lesions (tumoral intra-epithelial neoplasia) including intraductal papillary mucinous neoplasms, intraductal oncocytic papillary neoplasms, intraductal tubulopapillary neoplasms, intraductal papillary neoplasms of the bile duct and intracholecystic papillary neoplasms. Early detection and adequate treatment of these precursor lesions, especially the second group, have the potential to prevent pancreatobiliary cancer or at least improve its prognosis. In this review, we discuss their histopathology and recent updates on molecular profiling of these intraductal neoplasms of the pancreatobiliary tract. © 2023 John Wiley & Sons Ltd.
Keywords: clinical feature; histopathology; review; pancreatic neoplasms; intraductal papillary mucinous tumor; carcinoma, pancreatic ductal; pathology; carcinoma in situ; pancreas tumor; bile duct neoplasms; bile duct tumor; intraductal papillary mucinous neoplasm; pancreatic ductal carcinoma; pancreatic intraepithelial neoplasia; intraductal oncocytic papillary neoplasm; humans; prognosis; human; biliary intraepithelial neoplasia; intraductal tubulopapillary neoplasm; molecular fingerprinting; pancreatic duct; intraductal papillary neoplasm of the bile duct; biliary intra-epithelial neoplasia; intracholecystic papillary neoplasm; intraductal papillary neoplasm of bile duct; pancreatic intra-epithelial neoplasia; oncocytic tumor
Journal Title: Histopathology
Volume: 83
Issue: 4
ISSN: 0309-0167
Publisher: Wiley Blackwell  
Date Published: 2023-10-01
Start Page: 499
End Page: 508
Language: English
DOI: 10.1111/his.15003
PUBMED: 37455382
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165071058&doi=10.1111%2fhis.15003&partnerID=40&md5=72bbe822d96390e1865c41c8e2a1bb27
Notes: Review -- MSK corresponding author is Olca Basturk -- Source: Scopus
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MSK Authors
  1. Olca Basturk
    352 Basturk
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