Translating energy balance research from the bench to the clinic to the community: Parallel animal-human studies in cancer Review
| Authors: | Garcia, M. B.; Schadler, K. L.; Chandra, J.; Clinton, S. K.; Courneya, K. S.; Cruz-Monserrate, Z.; Daniel, C. R.; Dannenberg, A. J.; Demark-Wahnefried, W.; Dewhirst, M. W.; Fabian, C. J.; Hursting, S. D.; Irwin, M. L.; Iyengar, N. M.; McQuade, J. L.; Schmitz, K. H.; Basen-Engquist, K. |
| Review Title: | Translating energy balance research from the bench to the clinic to the community: Parallel animal-human studies in cancer |
| Abstract: | Advances in energy balance and cancer research to date have largely occurred in siloed work in rodents or patients. However, substantial benefit can be derived from parallel studies in which animal models inform the design of clinical and population studies or in which clinical observations become the basis for animal studies. The conference Translating Energy Balance from Bench to Communities: Application of Parallel Animal-Human Studies in Cancer, held in July 2021, convened investigators from basic, translational/clinical, and population science research to share knowledge, examples of successful parallel studies, and strong research to move the field of energy balance and cancer toward practice changes. This review summarizes key topics discussed to advance research on the role of energy balance, including physical activity, body composition, and dietary intake, on cancer development, cancer outcomes, and healthy survivorship. © 2023 The Authors. CA: A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society. |
| Keywords: | adult; review; nonhuman; neoplasm; neoplasms; animal; animals; animal experiment; animal model; exercise; cancer research; diet; population research; survivorship; physical activity; rodent; body composition; language; dietary intake; clinical observation; translational research; nutrition; energy balance; cancer survivorship; cancer; humans; human; male; female |
| Journal Title: | CA - A Cancer Journal for Clinicians |
| Volume: | 73 |
| Issue: | 4 |
| ISSN: | 0007-9235 |
| Publisher: | Wiley-Blackwell |
| Date Published: | 2023-07-01 |
| Start Page: | 425 |
| End Page: | 442 |
| Language: | English |
| DOI: | 10.3322/caac.21773 |
| PUBMED: | 36825928 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
