Validating the PROMIS cognitive function short form in cancer survivors Journal Article

   


Authors: Henneghan, A. M.; Van Dyk, K.; Zhou, X.; Moore, R. C.; Root, J. C.; Ahles, T. A.; Nakamura, Z. M.; Mandeblatt, J.; Ganz, P. A.
Article Title: Validating the PROMIS cognitive function short form in cancer survivors
Abstract: Purpose: The Patient-Reported Outcome Measurement Information System Cognitive Function Short Form 8a (PROMIS Cog) could provide a shorter, useful alternative to the often used Functional Assessment of Cancer Therapy – Cognition (FACT-Cog) in research and clinical care. This study aimed to determine the convergent validity and internal reliability of the PROMIS Cog in 3 separate samples of breast cancer survivors and to explore clinical cut points. Methods: Data from three samples of breast cancer survivors were used for this secondary analysis. Convergent validity was determined by evaluating correlation strength among the derived PROMIS Cog and measures of depression, anxiety, stress, fatigue, sleep, loneliness, the FACT-Cog. Clinical cut-points for the PROMIS Cog were determined by plotting the receiver operating characteristic curves. Results: 3 samples of breast cancer survivors (N = 471, N = 132, N = 90) were included. Absolute values of correlations demonstrating convergent validity ranged from 0.21 to 0.82, p’s < 0.001, and were comparable to correlations with the full FACT-Cog 18 item perceived cognitive impairments (PCI) scale. ROC curve plots indicated a clinical cut off < 34 for the combined sample. Conclusion: The 8-item PROMIS Cog demonstrated good convergent validity and internal reliability in breast cancer survivors, comparable to the 18-item FACT-Cog PCI. The PROMIS Cog 8a is a brief self-report measure that can be easily incorporated into cancer-related cognitive impairment research designs or used in clinical settings. © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Keywords: adult; aged; major clinical study; fatigue; sensitivity and specificity; reproducibility; reproducibility of results; quality of life; breast cancer; psychology; breast neoplasms; cancer survivor; self report; questionnaire; depression; breast tumor; cognition; intermethod comparison; cognitive defect; reliability; anxiety; loneliness; mental stress; psychometrics; psychometry; receiver operating characteristic; reference value; cancer survivors; complication; diagnostic test accuracy study; self-report; sleep quality; convergent validity; very elderly; humans; human; female; article; surveys and questionnaires; cancer-related cognitive impairment; functional assessment of cancer therapy cognitive function; internal reliability; promis cognition; cognitive impairment assessment; promis cognitive function short form 8a
Journal Title: Breast Cancer Research and Treatment
Volume: 201
Issue: 1
ISSN: 0167-6806
Publisher: Springer  
Date Published: 2023-08-01
Start Page: 139
End Page: 145
Language: English
DOI: 10.1007/s10549-023-06968-2
PUBMED: 37330430
PROVIDER: scopus
PMCID: PMC10729147
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85162218622&doi=10.1007%2fs10549-023-06968-2&partnerID=40&md5=2716e4cb4f27c0ca8ff87098b43fc0d2
Notes: Article -- Source: Scopus
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MSK Authors
  1. Tim A Ahles
    182 Ahles
  2. James Charles Root
    113 Root
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