Anal carcinoma, version 2.2023: NCCN Clinical Practice Guidelines in Oncology Guidelines

  


Authors: Benson, A. B. 3rd; Venook, A. P.; Al-Hawary, M. M.; Azad, N.; Chen, Y. J.; Ciombor, K. K.; Cohen, S.; Cooper, H. S.; Deming, D.; Garrido-Laguna, I.; Grem, J. L.; Randolph Hecht, J.; Hoffe, S.; Hubbard, J.; Hunt, S.; Hussan, H.; Jeck, W.; Johung, K. L.; Joseph, N.; Kirilcuk, N.; Krishnamurthi, S.; Maratt, J.; Messersmith, W. A.; Meyerhardt, J.; Miller, E. D.; Mulcahy, M. F.; Nurkin, S.; Overman, M. J.; Parikh, A.; Patel, H.; Pedersen, K.; Saltz, L.; Schneider, C.; Shibata, D.; Skibber, J. M.; Sofocleous, C. T.; Stotsky-Himelfarb, E.; Tavakkoli, A.; Willett, C. G.; Williams, G.; Algieri, F.; Gurski, L.; Stehman, K.
Title: Anal carcinoma, version 2.2023: NCCN Clinical Practice Guidelines in Oncology
Abstract: This discussion summarizes the NCCN Clinical Practice Guidelines for managing squamous cell anal carcinoma, which represents the most common histologic form of the disease. A multidisciplinary approach including physicians from gastroenterology, medical oncology, surgical oncology, radiation oncology, and radiology is necessary. Primary treatment of perianal cancer and anal canal cancer are similar and include chemoradiation in most cases. Follow-up clinical evaluations are recommended for all patients with anal carcinoma because additional curative-intent treatment is possible. Biopsy-proven evidence of locally recurrent or persistent disease after primary treatment may require surgical treatment. Systemic therapy is generally recommended for extrapelvic metastatic disease. Recent updates to the NCCN Guidelines for Anal Carcinoma include staging classification updates based on the 9th edition of the AJCC Staging System and updates to the systemic therapy recommendations based on new data that better define optimal treatment of patients with metastatic anal carcinoma. © 2023 Harborside Press. All rights reserved.
Keywords: squamous cell carcinoma; carcinoma, squamous cell; oncology; biopsy; medical oncology; anus neoplasms; anus tumor; anus carcinoma; humans; human; anal canal carcinoma
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 21
Issue: 6
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2023-06-01
Start Page: 653
End Page: 677
Language: English
DOI: 10.6004/jnccn.2023.0030
PUBMED: 37308125
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85163141944&doi=10.6004%2fjnccn.2023.0030&partnerID=40&md5=ef560f1bc7b5b4df224ce86066664cb0
Notes: Article -- Source: Scopus
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MSK Authors
  1. Leonard B Saltz
    791 Saltz
  2. Constantinos T Sofocleous
    245 Sofocleous
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