Osteoradionecrosis of the jaw: A mini review Review
| Authors: | Singh, A.; Huryn, J. M.; Kronstadt, K. L.; Yom, S. K.; Randazzo, J. R.; Estilo, C. L. |
| Review Title: | Osteoradionecrosis of the jaw: A mini review |
| Abstract: | Osteoradionecrosis (ORN) of the jaw is one of the most dreaded complications of head and neck radiation therapy. Despite the evolution of radiation treatment modalities, ORN continues to remain a therapeutic challenge and its etiopathogenesis still remains unclear. It is clinically characterized by exposed necrotic bone within the head and neck radiation field. Over the past years, several studies have reported on the definition, staging, incidence, etiology, and management of this oral complication. In this review, we summarize the literature on ORN and discuss our institutional experience and management strategies that aim to predict and mitigate risk for ORN. |
| Keywords: | cancer therapy; head and neck cancer; quality-of-life; neck-cancer; risk-factors; retrospective analysis; jaw; intensity modulated radiation therapy (imrt); modulated radiation-therapy; dental extractions; mandibular osteoradionecrosis; hyperbaric-oxygen; tooth-bearing regions; dosimetric distribution; osteoradionecrosis (orn); osteoradionecrosis of; oral complications of |
| Journal Title: | Frontiers in Oral Health |
| Volume: | 3 |
| ISSN: | 2673-4842 |
| Publisher: | Frontiers Media S.A. |
| Date Published: | 2022-01-01 |
| Start Page: | 980786 |
| Language: | English |
| ACCESSION: | WOS:000995164100001 |
| DOI: | 10.3389/froh.2022.980786 |
| PROVIDER: | wos |
| PMCID: | PMC9366306 |
| PUBMED: | 35967463 |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PubMed record and PDF. Corresponding author is MSK author Cherry L Estilo -- Source: Wos |
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