Frequently asked questions on Coronavirus disease 2019 vaccination for hematopoietic cell transplantation and chimeric antigen receptor T-cell recipients from the American Society for Transplantation and Cellular Therapy and the American Society of Hematology Guidelines

   

Authors:	Khawaja, F.; Papanicolaou, G.; Dadwal, S.; Pergam, S. A.; Wingard, J. R.; El Boghdadly, Z.; Abidi, M. Z.; Waghmare, A.; Shahid, Z.; Michaels, L.; Hill, J. A.; Kamboj, M.; Boeckh, M.; Auletta, J. J.; Chemaly, R. F.
Title:	Frequently asked questions on Coronavirus disease 2019 vaccination for hematopoietic cell transplantation and chimeric antigen receptor T-cell recipients from the American Society for Transplantation and Cellular Therapy and the American Society of Hematology
Abstract:	Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), disproportionately affects immunocompromised and elderly patients. Not only are hematopoietic cell transplan-tation (HCT) and chimeric antigen receptor (CAR) T-cell recipients at greater risk for severe COVID-19 and COVID-19-related complications, but they also may experience suboptimal immune responses to currently available COVID-19 vaccines. Optimizing the use, timing, and number of doses of the COVID-19 vaccines in these patients may provide better protection against SARS-CoV-2 infection and better outcomes after infection. To this end, cur-rent guidelines for COVID-19 vaccination in HCT and CAR T-cell recipients from the American Society of Trans-plantation and Cellular Therapy Transplant Infectious Disease Special Interest Group and the American Society of Hematology are provided in a frequently asked questions format. (c) 2022 The American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Keywords:	influenza vaccination; safety; children; vaccines; efficacy; united-states; responses; bone marrow transplant; infections; sct; hematopoietic cell transplant; chimeric antigen; car t-cell; coronavirus disease 2019; covid-19; sars-cov-2; mrna vaccine; adenoviral vector vaccine; receptor t-cell; severe acute respiratory syn; drome; coronavirus 2; vaccine safety
Journal Title:	Transplantation and Cellular Therapy
Volume:	29
Issue:	1
ISSN:	2666-6375
Publisher:	Elsevier Inc.
Date Published:	2023-01-01
Start Page:	10
End Page:	18
Language:	English
ACCESSION:	WOS:000971753000001
DOI:	10.1016/j.jtct.2022.10.010
PROVIDER:	wos
PMCID:	PMC9584756
PUBMED:	36273782
Notes:	Article -- Source: Wos

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