Breast surgical oncology epidemiologic research: A guide and comparison of four national databases Journal Article

   


Authors: Rubenstein, R. N.; Nelson, J. A.; Azoury, S. C.; Shamsunder, M. G.; Haglich, K.; Yin, S.; Stern, C. S.; Matros, E.
Article Title: Breast surgical oncology epidemiologic research: A guide and comparison of four national databases
Abstract: Background: National databases are a rich source of epidemiologic data for breast surgical oncology research. However, these databases differ in the demographic, surgical, and oncologic variables provided. This study aimed to compare the strengths and limitations of four national databases in the context of breast surgical oncology research. Methods: The study comprised a descriptive analysis of four national databases (the National Surgical Quality Improvement Program [NSQIP], the Nationwide Inpatient Sample [NIS], the Surveillance, Epidemiology and End Results [SEER] program, and the National Cancer Database [NCDB]) to assess their strengths and limitations in the context of breast surgical oncology. The study assessed the data available in each database for female patients with a breast cancer diagnosis between 2007 and 2017, and compared patient age, ethnicity, and race distributions. Results: Data from 3.9 million female patients were examined, with most patients being between 60 and 69 years of age, non-Hispanic, and white. Age, ethnicity, and race distributions were similar in the databases. The NSQIP includes data on operative details, comorbidities, and postoperative outcomes. The NIS provides health services and inpatient utilization information, but does not evaluate outpatient procedures. The SEER program provides population-based oncologic detail including stage, histology, and neoadjuvant/adjuvant treatment. The NCDB offers hospital-based oncologic information and the largest population in the study period, with approximately 2.5 million breast cancer patients. Conclusion: Epidemiologic datasets offer tremendous potential for the examination of oncologic breast surgery, with each database providing unique data useful for addressing different epidemiologic questions. Understanding the strengths and limitations of each database creates a more efficient and productive research environment. © 2023, Society of Surgical Oncology.
Keywords: retrospective studies; united states; breast neoplasms; retrospective study; postoperative complication; postoperative complications; breast tumor; factual database; databases, factual; ethnicity; surgical oncology; humans; human; female
Journal Title: Annals of Surgical Oncology
Volume: 30
Issue: 4
ISSN: 1068-9265
Publisher: Springer  
Date Published: 2023-04-01
Start Page: 2069
End Page: 2084
Language: English
DOI: 10.1245/s10434-022-12890-6
PUBMED: 36600098
PROVIDER: scopus
PMCID: PMC10033365
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85143886304&doi=10.1245%2fs10434-022-12890-6&partnerID=40&md5=0486cd27657ba5eb07b372e60f7ffc13
Notes: Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK corresponding authors are Jonas Nelson and Evan Matros -- Export Date: 1 May 2023 -- Source: Scopus
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MSK Authors
  1. Carrie Stern
    44 Stern
  2. Evan Matros
    208 Matros
  3. Jonas Allan Nelson
    218 Nelson
  4. Meghana G Shamsunder
    43 Shamsunder
  5. Robyn Rubenstein
    26 Rubenstein
  6. Shen Yin
    11 Yin
  7. Kathryn Ann Haglich
    27 Haglich
  8. Said Charbel Azoury
    10 Azoury
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