Outcomes following free fibula physeal transfer for pediatric proximal humerus reconstruction: An international multi-institutional study Journal Article


Authors: Azoury, S. C.; Shammas, R. L.; Othman, S.; Sergesketter, A.; Brigman, B. E.; Nguyen, J. C.; Arkader, A.; Weber, K. L.; Erdmann, D.; Levin, L. S.; Kovach, S. J.; Innocenti, M.
Article Title: Outcomes following free fibula physeal transfer for pediatric proximal humerus reconstruction: An international multi-institutional study
Abstract: Background: Vascularized fibula epiphyseal flap was first described in 1998 for proximal humeral reconstruction in children/infants. The authors aim to review their international, multi-institutional, long-term outcomes. Methods: An international, multi-institutional review (2004 to 2020) was conducted of patients younger than 18 years undergoing free vascularized fibula epiphyseal transfer for proximal humeral reconstruction. Donor- and recipient-site complications, pain, and final ambulatory status were reviewed. Growth of the transferred bone was assessed under the guidance of a pediatric musculoskeletal radiologist. Results: Twenty-seven patients were included with a median age of 7 years (range, 2 to 13 years). Average follow-up was 120 ± 87.4 months. There were two flap failures (7.4%). Recipient-site complications included fracture [n = 11 (40.7%)], avascular necrosis of the fibula head [n = 1 (3.7%)], fibular head avulsion [n = 1 (3.7%)], infection [n = 1 (3.7%)], and hardware failure [n = 1 (3.7%)]. Operative fixation was necessary in one patient with a fracture. The case of infection necessitated fibula explantation 2 years postoperatively, and ultimately, prosthetic reconstruction. Sixteen patients developed peroneal nerve palsy (59.3%): 13 of these cases resolved within 1 year (81% recovery), and three were permanent (11.1%). One patient (3.7%) complained of upper extremity pain. Longitudinal growth was confirmed in all but three cases [n = 24 (88.9%)] at an average rate of 0.83 ± 0.25 cm/year. Conclusions: The vascularized fibula epiphysis for proximal humerus reconstruction in children preserves the potential for future growth and an articular surface for motion. Peroneal nerve palsy is common following harvest, although this is often transient. Future efforts should be geared toward reducing postoperative morbidity. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV. © 2023 Lippincott Williams and Wilkins. All rights reserved.
Keywords: adolescent; child; preschool child; treatment outcome; bone neoplasms; child, preschool; bone tumor; fracture; humerus; bone transplantation; retrospective studies; clinical trial; pain; vascularization; retrospective study; multicenter study; fractures, bone; epiphysis; fibula; paralysis; humans; human; epiphyses
Journal Title: Plastic and Reconstructive Surgery
Volume: 151
Issue: 4
ISSN: 0032-1052
Publisher: Lippincott Williams & Wilkins  
Date Published: 2023-04-01
Start Page: 805
End Page: 813
Language: English
DOI: 10.1097/prs.0000000000010001
PUBMED: 36729876
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 May 2023 -- Source: Scopus
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  1. Said Charbel Azoury
    10 Azoury