Paravertebral blocks in tissue expander breast reconstruction: Propensity-matched analysis of opioid consumption and patient outcomes Journal Article


Authors: Shamsunder, M. G.; Chu, J. J.; Taylor, E.; Polanco, T. O.; Allen, R. J. Jr; Moo, T. A.; Disa, J. J.; Mehrara, B. J.; Tokita, H. K.; Nelson, J. A.
Article Title: Paravertebral blocks in tissue expander breast reconstruction: Propensity-matched analysis of opioid consumption and patient outcomes
Abstract: Background: The paravertebral block (PVB) is an adjunctive perioperative pain control method for patients undergoing breast reconstruction that may improve perioperative pain control and reduce narcotic use. This study determined the efficacy of preoperative PVBs for perioperative pain management in patients undergoing tissue expander breast reconstruction. Methods: A retrospective review was performed of patients who underwent tissue expander breast reconstruction from December of 2017 to September of 2019. Two patients with PVBs were matched using propensity scoring to one no-block patient. Perioperative analgesic use, pain severity scores on days 2 to 10 after discharge, and BREAST-Q Physical Well-Being scores before surgery and at 2 weeks, 6 weeks, and 3 months after surgery were compared between the two groups. Results: The propensity-matched cohort consisted of 471 patients (314 PVB and 157 no block). The PVB group used significantly fewer morphine milligram equivalents than the no-block group (53.7 versus 69.8; P < 0.001). Average daily postoperative pain severity scores were comparable, with a maximum difference of 0.3 points on a 0-point to 4-point scale. BREAST-Q Physical Well-Being scores were significantly higher for the PVB group than the no-block group at 6 weeks after surgery (60.6 versus 51.0; P = 0.015) but did not differ significantly at 2 weeks or 3 months after surgery. Conclusions: PVBs may help reduce perioperative opioid requirements but did not reduce pain scores after discharge when used as part of an expander-based reconstruction perioperative pain management protocol. Continued research should examine additional or alternative regional block procedures as well as financial cost and potential long-term impact of PVBs. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III. © 2023 Lippincott Williams and Wilkins. All rights reserved.
Keywords: breast reconstruction; mammaplasty; tissue expansion devices; narcotic analgesic agent; analgesics, opioid; postoperative pain; pain, postoperative; nerve block; tissue expander; procedures; humans; human
Journal Title: Plastic and Reconstructive Surgery
Volume: 151
Issue: 4
ISSN: 0032-1052
Publisher: Lippincott Williams & Wilkins  
Date Published: 2023-04-01
Start Page: 542e
End Page: 551e
Language: English
DOI: 10.1097/prs.0000000000009981
PUBMED: 36729942
PROVIDER: scopus
PMCID: PMC10065883
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Jonas A. Nelson -- Source: Scopus
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MSK Authors
  1. Joseph Disa
    262 Disa
  2. Babak Mehrara
    448 Mehrara
  3. Tracy-Ann Moo
    96 Moo
  4. Jonas Allan Nelson
    209 Nelson
  5. Hanae Tokita
    27 Tokita
  6. Thais O Polanco
    24 Polanco
  7. Jacqueline J. Chu
    27 Chu
  8. Erin Mcdonald Taylor
    1 Taylor