Gestational trophoblastic disease Book Section
| Authors: | Elias, K. M.; Ellenson, L. H.; Horowitz, N. S.; Berkowitz, R. S. |
| Editors: | Frumovitz, M.; Leitao, M. M. Jr; Ramalingam, P. |
| Article/Chapter Title: | Gestational trophoblastic disease |
| Abstract: | Gestational trophoblastic disease (GTD) refers to a category of lesions characterized by abnormal proliferation of placental trophoblasts. Benign forms of GTD include exaggerated placental site, atypical placental site nodule, and partial and complete hydatidiform mole. Malignant forms of GTD are referred to as gestational trophoblastic neoplasia (GTN). GTN includes invasive mole, choriocarcinoma, and the very rare placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT). Unique among gynecologic cancers, GTN does not require a definitive histopathologic diagnosis. The diagnosis can also be made with laboratory tests alone when there is a persistent elevation of human chorionic gonadotropin (hCG) after evacuation of a molar pregnancy. © 2023 Elsevier Inc. All rights reserved. |
| Keywords: | chemotherapy; surgery; choriocarcinoma; gestational trophoblastic neoplasia; gestational trophoblastic disease; complete hydatidiform mole; invasive mole; epithelioid trophoblastic tumor (ett); partial hydatidiform mole; placental site trophoblastic tumor (pstt) |
| Book Title: | Diagnosis and Treatment of Rare Gynecologic Cancers |
| ISBN: | 978-0-323-82938-0 |
| Publisher: | Elsevier Inc. |
| Publication Place: | Amsterdam, Netherlands |
| Date Published: | 2023-01-01 |
| Start Page: | 345 |
| End Page: | 361 |
| Language: | English |
| DOI: | 10.1016/b978-0-323-82938-0.00021-5 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 21, part of "Section E: Gestational trophoblastic disease" -- Export Date: 1 May 2023 -- Source: Scopus |
