Shedding light on PARP inhibitor response through functional imaging Editorial

   


Authors: Liu, Y. L.; Zamarin, D.
Title: Shedding light on PARP inhibitor response through functional imaging
Abstract: Functional PET imaging using a PARP inhibitor (PARPi) analog may serve as an early, dynamic biomarker of response to PARPi therapy in high-grade serous ovarian cancer. Clinically, this could help to rapidly identify PARPi nonresponders, thereby maximizing efficacy and avoiding toxicities of futile treatments. See related article by Pantel et al., p. 1515. ©2023 American Association for Cancer Research.
Keywords: antineoplastic agents; antineoplastic agent; ovarian neoplasms; biomarkers; biological marker; diagnostic imaging; pilot study; pilot projects; ovary tumor; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor; humans; human; female; poly(adp-ribose) polymerase inhibitors
Journal Title: Clinical Cancer Research
Volume: 29
Issue: 8
ISSN: 1078-0432
Publisher: American Association for Cancer Research  
Date Published: 2023-04-15
Start Page: 1384
End Page: 1386
Language: English
DOI: 10.1158/1078-0432.Ccr-22-3711
PUBMED: 36700799
PROVIDER: scopus
PMCID: PMC10106371
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85152595647&doi=10.1158%2f1078-0432.CCR-22-3711&partnerID=40&md5=512a3812fc26436c354dec1c246ebd1a
Notes: Export Date: 1 May 2023 -- Source: Scopus
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  1. Ying Liu
    105 Liu
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