A modified net reclassification improvement statistic Journal Article


Author: Heller, G.
Article Title: A modified net reclassification improvement statistic
Abstract: The continuous net reclassification improvement (NRI) statistic is a popular model change measure that was developed to assess the incremental value of new factors in a risk prediction model. Two prominent statistical issues identified in the literature call the utility of this measure into question: (1) it is not a proper scoring function and (2) it has a high false positive rate when testing whether new factors contribute to the risk model. For binary response regression models, these subjects are interrogated and a modification of the continuous NRI, guided by the likelihood-based score residual, is proposed to address these issues. Within a nested model framework, the modified NRI may be viewed as a distance measure between two risk models. An application of the modified NRI is illustrated using prostate cancer data. © 2023 Elsevier B.V.
Keywords: nested models; proper score; binary response model; l<sub>1</sub> distance; valid test
Journal Title: Journal of Statistical Planning and Inference
Volume: 227
ISSN: 0378-3758
Publisher: Elsevier B.V.  
Date Published: 2023-12-01
Start Page: 18
End Page: 33
Language: English
DOI: 10.1016/j.jspi.2023.03.001
PROVIDER: scopus
PMCID: PMC10079138
PUBMED: 37035267
DOI/URL:
Notes: Article --MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is Glenn Heller -- Source: Scopus
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  1. Glenn Heller
    399 Heller