ST elevation myocardial infarction - National trend analysis with mortality differences in outcomes based on day of hospitalization Journal Article


Authors: Jha, A.; Ojha, C. P.; Bhattad, P. B.; Sharma, A.; Thota, A.; Mishra, A. K.; Krishnan, A. M.; Roumia, M.
Article Title: ST elevation myocardial infarction - National trend analysis with mortality differences in outcomes based on day of hospitalization
Abstract: Background Patientswho present with acute ST elevation myocardial infarction (STEMI) need emergent revascularization. Our study aims to investigate the outcomes in patients with STEMI admitted during weekends versus weekdays. Methods We conducted a retrospective analysis of the nationwide inpatient sample database. Patients with an admitting diagnosis of STEMI identified by the International Classification of Disease code for the year 2016 were analyzed. A weighted descriptive analysis was performed to generate national estimates. Patients admitted over the weekend were compared to those admitted over the weekday. Patients were stratified by demographic and clinical factors including the Elixhauser comorbidity index. The primary outcome was in-hospital mortality and secondary outcomes were percutaneous coronary intervention (PCI) utilization rate, rate of transfer-out, length of stay (LOS), and total hospital charges. Statistical analysis including linear and logistic regression was performed using STATA. Results A total of 163 715 adult patients were admitted with STEMI, of which 27.9% (45 635) were admitted over the weekend. There were 76.2% Caucasians, 9.3% African Americans, and 8.0% Hispanics. Mean age of the patients was 63.2 years (95% CI, 62.9-63.5) for the weekend group and 63.7 years (95% CI, 63.5-63.9) for weekday admissions. The majority of the patients in both groups had Medicare (43.7% and 45.8% on weekends and weekdays, respectively; P = 0.0047). After adjusting for age, sex, race, income, Elixhauser comorbidity index, PCI use, hospital location, teaching status, and bed size, mortality was not significantly different in weekend versus weekday admissions (odds ratios 1.04; P = 0.498; 95% CI, 0.93-1.16). There was no significant difference in mean total charge per admission during the weekend versus weekday admissions ($107 093 versus $106 869; P = 0.99.) Mean LOS was 4.1 days for both groups (P = 0.81). Conclusions There were no significant differences in mortality, LOS, or total hospital charge in STEMI patients being admitted during the weekend versus weekdays. © 2023 Lippincott Williams and Wilkins. All rights reserved.
Keywords: adult; controlled study; aged; middle aged; retrospective studies; major clinical study; united states; outcome assessment; disease association; clinical assessment; cohort analysis; retrospective study; time factors; health care utilization; medicare; length of stay; hospitalization; medical education; comorbidity; hospital admission; epidemiology; trend study; african american; hospitalization cost; caucasian; international classification of diseases; hispanic; descriptive research; patient transport; hospital mortality; lowest income group; hospital bed utilization; patient admission; demographics; percutaneous coronary intervention; time factor; acute coronary syndrome; in-hospital mortality; hospital charge; st segment elevation myocardial infarction; humans; human; male; female; article; household income; elixhauser comorbidity index; highest income group; st elevation myocardial infarction; hospital length of stay; national inpatient dataset; percutaneous coronary interventions
Journal Title: Coronary Artery Disease
Volume: 34
Issue: 2
ISSN: 0954-6928
Publisher: Lippincott Williams & Wilkins  
Date Published: 2023-03-01
Start Page: 119
End Page: 126
Language: English
DOI: 10.1097/mca.0000000000001211
PUBMED: 36720020
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 March 2023 -- Source: Scopus
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  1. Ajit Karan Thota
    6 Thota