American Radium Society (ARS) Appropriate Use Criteria (AUC) for extrahepatic cholangiocarcinoma Review


Authors: Tchelebi, L. T.; Jethwa, K. R.; Levy, A. T.; Anker, C. J.; Kennedy, T.; Grodstein, E.; Hallemeier, C. L.; Jabbour, S. K.; Kim, E.; Kumar, R.; Lee, P.; Small, W. Jr; Williams, V. M.; Sharma, N.; Russo, S.
Review Title: American Radium Society (ARS) Appropriate Use Criteria (AUC) for extrahepatic cholangiocarcinoma
Abstract: Although uncommon, extrahepatic cholangiocarcinoma (EHCC) is a deadly malignancy, and the treatment approaches remain controversial. While surgery remains the only cure, few patients are candidates for resection up front, and there are high rates of both local and distant failure following resection. Herein, we systematically review the available evidence regarding treatment approaches for patients with EHCC, including surgery, radiation, and chemotherapy. The evidence regarding treatment outcomes was assessed using the Population, Intervention, Comparator, Outcome, and Study design (PICOS) framework. A summary of recommendations based on the available literature is outlined for specific clinical scenarios encountered by providers in the clinic to guide the management of these patients. Copyright © 2022 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.Unauthorized reproduction of this article is prohibited.
Keywords: adult; controlled study; treatment outcome; cancer surgery; cisplatin; fluorouracil; area under the curve; cancer combination chemotherapy; systemic therapy; united states; capecitabine; gemcitabine; paclitaxel; cancer radiotherapy; neoadjuvant therapy; chemotherapy; nuclear magnetic resonance imaging; pancreaticoduodenectomy; computer assisted tomography; ca 19-9 antigen; pathology; postoperative complication; bilirubin; systematic review; adjuvant chemotherapy; medical society; brachytherapy; surgery; jaundice; surgical mortality; consensus development; contrast medium; radiation therapy; area under curve; bile duct carcinoma; bile duct neoplasms; bile ducts, intrahepatic; cholangiocarcinoma; hyperbilirubinemia; oxaliplatin; photodynamic therapy; gallbladder cancer; bilirubin blood level; meta analysis; iridium 192; bile duct cancer; surgical margin; superior mesenteric artery; liver graft; intrahepatic bile duct; radium; extrahepatic cholangiocarcinoma; humans; human; male; female; article; liver transplant
Journal Title: American Journal of Clinical Oncology
Volume: 46
Issue: 2
ISSN: 0277-3732
Publisher: Lippincott Williams & Wilkins  
Date Published: 2023-02-01
Start Page: 73
End Page: 84
Language: English
DOI: 10.1097/coc.0000000000000969
PUBMED: 36534388
PROVIDER: scopus
PMCID: PMC9855763
DOI/URL:
Notes: Article -- Export Date: 1 March 2023 -- Source: Scopus
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