Mitigation of gastrointestinal graft-versus-host disease with tocilizumab prophylaxis is accompanied by preservation of microbial diversity and attenuation of enterococcal domination Research Letter


Authors: Chhabra, S.; Szabo, A.; Clurman, A.; McShane, K.; Waters, N.; Eastwood, D.; Samanas, L.; Fei, T.; Armijo, G.; Abedin, S.; Longo, W.; Hari, P.; Hamadani, M.; Shah, N. N.; Runaas, L.; Jerkins, J. H.; van den Brink, M.; Peled, J. U.; Drobyski, W. R.
Title: Mitigation of gastrointestinal graft-versus-host disease with tocilizumab prophylaxis is accompanied by preservation of microbial diversity and attenuation of enterococcal domination
Keywords: busulfan; mortality; neutropenia; methotrexate; letter; cell proliferation; multiple myeloma; morbidity; hematopoietic stem cell transplantation; chronic myeloid leukemia; monoclonal antibody; myelodysplastic syndrome; prophylaxis; escherichia coli; graft versus host reaction; interleukin 6; allogeneic hematopoietic stem cell transplantation; enterococcus; intestine flora; gastrointestinal tract; tacrolimus; graft vs host disease; influenza; feces analysis; phylogeny; bronchiolitis obliterans; microbial diversity; tocilizumab; antibodies, monoclonal, humanized; humans; human; hierarchical clustering; dysbiosis; mitigation; capnocytophaga sputigena; streptococcus oralis; turnover rate
Journal Title: Haematologica
Volume: 108
Issue: 1
ISSN: 0390-6078
Publisher: Ferrata Storti Foundation  
Date Published: 2023-01-01
Start Page: 250
End Page: 256
Language: English
DOI: 10.3324/haematol.2022.281309
PUBMED: 36106394
PROVIDER: scopus
PMCID: PMC9827178
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF and PubMed record. -- Source: Scopus
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MSK Authors
  1. Jonathan U Peled
    155 Peled
  2. Annelie G Clurman
    27 Clurman
  3. Gabriel Armijo
    17 Armijo
  4. Nicholas R. Waters
    12 Waters
  5. Teng Fei
    40 Fei