Evidence-Based Minireview: Full dose, modified dose, or no anticoagulation for patients with cancer and acute VTE and thrombocytopenia Review


Authors: Patell, R.; Zwicker, J. I.
Review Title: Evidence-Based Minireview: Full dose, modified dose, or no anticoagulation for patients with cancer and acute VTE and thrombocytopenia
Abstract: Co-incident venous thromboembolism and thrombocytopenia are frequent in patients with active malignancies. The optimal approach for anticoagulation in patients with cancer and thrombocytopenia is not established. Different strategies are often utilized including dose-reduced anticoagulation dictated by degree of thrombocytopenia or transfusing platelets in order to facilitate therapeutic anticoagulation. This minireview provides an overview of the data and we outline our approach toward anticoagulation in patients with venous thromboembolism and thrombocytopenia in the setting of cancer. Copyright © 2022 by The American Society of Hematology.
Keywords: neoplasm; neoplasms; bleeding; thrombocytopenia; anticoagulants; venous thromboembolism; anticoagulant agent; complication; hemorrhage; humans; human
Journal Title: Hematology-American Society of Hematology Education Program
Volume: 2022
Issue: 1
ISSN: 1520-4391
Publisher: American Society of Hematology  
Date Published: 2022-12-09
Start Page: 312
End Page: 315
Language: English
DOI: 10.1182/hematology.2022000411
PUBMED: 36485075
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 3 January 2023 -- Source: Scopus
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  1. Jeffrey Zwicker
    35 Zwicker
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