Authors: | Rosen, E.; Drilon, A.; Chakravarty, D. |
Review Title: | Precision oncology: 2022 in review |
Abstract: | This article presents a review of the major advances and future implications in precision oncology accomplished in 2022 and centers on three primary pillars: advances in (i) rational drug design, (ii) study design, and (iii) novel biomarkers. © 2022 American Association for Cancer Research. |
Keywords: | immunohistochemistry; protein expression; gene mutation; overall survival; somatic mutation; genetics; review; erlotinib; pancreas cancer; research design; methodology; neoplasm; neoplasms; tumor associated leukocyte; mass spectrometry; biological marker; dacarbazine; ipilimumab; cancer immunotherapy; melanoma; progression free survival; apoptosis; multiple myeloma; breast cancer; epidermal growth factor receptor 2; in vivo study; in vitro study; drug design; oncology; proteomics; tumor antigen; docetaxel; hyperglycemia; in situ hybridization; immunological tolerance; systematic review; carcinogenicity; tumor cell; medical oncology; chimeric antigen receptor; bile duct carcinoma; thyroid cancer; leiomyosarcoma; trastuzumab; uvea melanoma; tumor gene; thermostability; fibroblast growth factor receptor 2; pertuzumab; personalized medicine; non small cell lung cancer; langerhans cell histiocytosis; genotyping; phase 2 clinical trial (topic); phase 3 clinical trial (topic); phase 1 clinical trial (topic); acute myeloid leukemia; crizotinib; vemurafenib; trametinib; high throughput sequencing; nivolumab; humans; human; article; precision medicine; pembrolizumab; alectinib; alpelisib; durvalumab; brigatinib; lorlatinib; sotorasib |
Journal Title: | Cancer Discovery |
Volume: | 12 |
Issue: | 12 |
ISSN: | 2159-8274 |
Publisher: | American Association for Cancer Research |
Date Published: | 2022-12-01 |
Start Page: | 2747 |
End Page: | 2753 |
Language: | English |
DOI: | 10.1158/2159-8290.Cd-22-1154 |
PUBMED: | 36458431 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 3 January 2023 -- Source: Scopus |