Less, but better: A simplified design for T cell redirection and conditional payload delivery Editorial

  


Authors: Kropp, K. N.; Klebanoff, C. A.
Title: Less, but better: A simplified design for T cell redirection and conditional payload delivery
Abstract: Combining immune receptor engineering with conditional expression of accessory molecules holds great promise for advancing the field of cell-based immunotherapies. In this issue of Cancer Cell, Smole et al. introduce a modular single vector system to simultaneously redirect T cell specificity toward cancer antigens while achieving activation-gated delivery of customizable payloads. Copyright © 2022 Elsevier Inc. All rights reserved.
Keywords: neoplasm; neoplasms; t lymphocyte; t-lymphocytes; immunotherapy; humans; human
Journal Title: Cancer Cell
Volume: 40
Issue: 12
ISSN: 1535-6108
Publisher: Cell Press  
Date Published: 2022-12-12
Start Page: 1454
End Page: 1456
Language: English
DOI: 10.1016/j.ccell.2022.11.012
PUBMED: 36513045
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144139979&doi=10.1016%2fj.ccell.2022.11.012&partnerID=40&md5=f87643184dc777b02fda0b6575ea696f
Notes: Article -- Export Date: 3 January 2023 -- Source: Scopus
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MSK Authors
  1. Christopher A Klebanoff
    58 Klebanoff
  2. Korbinian Nepomuk Kropp
    2 Kropp
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