"Knock me out": The challenges of managing pain due to cutaneous T cell lymphomas: A case report Journal Article


Authors: Pandey, S.; Dolan, A.; Norton-Westbrook, M.; Desai, A. V.
Article Title: "Knock me out": The challenges of managing pain due to cutaneous T cell lymphomas: A case report
Abstract: Cutaneous T cell lymphomas are associated with distressing symptoms, including pain and pruritus that negatively impact quality of life. Early involvement of palliative care can provide relief of symptoms and address multifaceted distress. This case highlights the complex management of cutaneous T cell lymphoma pain and associated symptoms, including existential and psychosocial distress. Our patient required frequent titration and rotation of high-dose opioids and adjuvant analgesics, ultimately requiring transfer to the intensive care unit for analgosedation. Total skin loss and disease complications led to his death after a compassionate withdrawal of life support. Cutaneous T cell lymphoma pain can be successfully managed with an interdisciplinary approach, early palliative care, and aggressive pain management. Complications from advanced disease, superinfection, and multidimensional distress complicate the efficacy of a multimodal analgesic approach. Further research is needed to deepen our understanding of how to optimally alleviate suffering within this vulnerable population.
Keywords: case report; palliative care; quality of life; pain; skin neoplasms; palliative therapy; cutaneous t cell lymphoma; skin tumor; methadone; analgesics; analgesia; analgesic agent; pain management; end of life; ketamine; complication; lymphoma, t-cell, cutaneous; humans; human; total pain
Journal Title: Journal of Palliative Medicine
Volume: 25
Issue: 11
ISSN: 1096-6218
Publisher: Mary Ann Liebert, Inc  
Date Published: 2022-11-01
Start Page: 1740
End Page: 1746
Language: English
DOI: 10.1089/jpm.2021.0561
PUBMED: 35420490
PROVIDER: scopus
PMCID: PMC9836697
DOI/URL:
Notes: Article -- Export Date: 1 December 2022 -- Source: Scopus
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  1. Andrea J Dolan
    3 Dolan
  2. Anjali Varma Desai
    25 Desai
  3. Shila Pandey
    15 Pandey