Author: | Peled, J. U. |
Title: | Xylose versus Bacteroides in graft-versus-host |
Abstract: | In a recent Cell paper, Hayase et al. define a mechanistic link between a carbapenem antibiotic and graft-versus-host disease (GVHD) following hematopoietic cell transplantation. Bacteroides thetaiotaomicron was observed to induce degradation of colonic mucus, an effect that was reversed by treatment with xylose, which served as a prebiotic to reduce mortality. © 2022 Elsevier Inc. |
Keywords: | transplantation, homologous; mortality; nonhuman; note; hematopoietic stem cell transplantation; graft versus host reaction; intestine flora; graft vs host disease; allotransplantation; degradation; colon mucosa; bacteroides; carbapenem; prebiotic agent; humans; human; xylose; bacteroides thetaiotaomicron; host microbe interaction |
Journal Title: | Cell Host & Microbe |
Volume: | 30 |
Issue: | 11 |
ISSN: | 1931-3128 |
Publisher: | Cell Press |
Date Published: | 2022-11-09 |
Start Page: | 1510 |
End Page: | 1511 |
Language: | English |
DOI: | 10.1016/j.chom.2022.10.007 |
PUBMED: | 36356567 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Note -- Export Date: 1 December 2022 -- Source: Scopus |