Xylose versus Bacteroides in graft-versus-host Editorial


Author: Peled, J. U.
Title: Xylose versus Bacteroides in graft-versus-host
Abstract: In a recent Cell paper, Hayase et al. define a mechanistic link between a carbapenem antibiotic and graft-versus-host disease (GVHD) following hematopoietic cell transplantation. Bacteroides thetaiotaomicron was observed to induce degradation of colonic mucus, an effect that was reversed by treatment with xylose, which served as a prebiotic to reduce mortality. © 2022 Elsevier Inc.
Keywords: transplantation, homologous; mortality; nonhuman; note; hematopoietic stem cell transplantation; graft versus host reaction; intestine flora; graft vs host disease; allotransplantation; degradation; colon mucosa; bacteroides; carbapenem; prebiotic agent; humans; human; xylose; bacteroides thetaiotaomicron; host microbe interaction
Journal Title: Cell Host & Microbe
Volume: 30
Issue: 11
ISSN: 1931-3128
Publisher: Cell Press  
Date Published: 2022-11-09
Start Page: 1510
End Page: 1511
Language: English
DOI: 10.1016/j.chom.2022.10.007
PUBMED: 36356567
PROVIDER: scopus
DOI/URL:
Notes: Note -- Export Date: 1 December 2022 -- Source: Scopus
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  1. Jonathan U Peled
    154 Peled