Quality issues in diagnostic immunohistochemistry in breast pathology Review
| Authors: | Hoda, R. S.; Brogi, E.; Wen, H. Y. |
| Review Title: | Quality issues in diagnostic immunohistochemistry in breast pathology |
| Abstract: | Immunohistochemistry techniques have been incorporated into surgical pathology for nearly a half-century and have since become intimately intertwined with its practice. In the realm of breast pathology, immunohistochemistry serves several purposes, including providing crucial prognostic and predictive data. Among its other applications, assessment of stromal invasion and establishment of mammary origin are crucial from a diagnostic standpoint. In these regards, sole reliance on immunohistochemistry may lead to misdiagnosis. In this review, we highlight pitfalls of immunohistochemistry commonly encountered in the practice of breast pathology and emphasize the importance of careful histopathological evaluation. © 2022 |
| Keywords: | immunohistochemistry; breast; pathology; breast neoplasms; tumor marker; diagnostic errors; breast tumor; diagnosis; pathology, surgical; approach; procedures; humans; human; female; biomarkers, tumor |
| Journal Title: | Pathobiology |
| Volume: | 89 |
| Issue: | 5 |
| ISSN: | 1015-2008 |
| Publisher: | S. Karger AG |
| Date Published: | 2022-10-01 |
| Start Page: | 324 |
| End Page: | 333 |
| Language: | English |
| DOI: | 10.1159/000522538 |
| PUBMED: | 35443240 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 November 2022 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work