Cancer clinical trial patient-participants’ perceptions about provider communication and dropout intentions Journal Article


Authors: Zhou, Q.; Ratcliffe, S. J.; Grady, C.; Wang, T.; Mao, J. J.; Ulrich, C. M.
Article Title: Cancer clinical trial patient-participants’ perceptions about provider communication and dropout intentions
Abstract: Objective: To study the relationship between cancer patient/research participants' perceptions of communication with their research nurse and doctor and (1) participants’ thoughts of dropping out from their cancer clinical trials (CCTs), (2) how informed they felt before and during their clinical trial participation, and (3) trust in their researchers. Methods: We surveyed 110 adult cancer patients who were enrolled in cancer clinical trials by using 15 modified items from the Medical Communication Competence Scale measuring information exchange and relational communication. Retention was measured by two items: ever thought about dropping out (yes/no) and likelihood of remaining enrolled in the clinical trial (5-point Likert item). We asked how well informed about the trial participants felt at enrollment, at the date they filled out the survey, and about changes in the trial. Results: Patient-participants with thoughts of dropping out from their CCTs rated their communication with research doctors lower than those who did not have thoughts of dropping out (4.14 versus 4.46, t = 2.22, p = 0.03). Patient-participants' intention to remain enrolled was correlated with more favorable scores on relational communication (such as contributing to a trusting relationship and showing compassion) with research doctors (r = 0.20, p = 0.04) and nurses (r = 0.25, p = 0.01). Communication with doctors was also associated with how informed patient-participants felt during their clinical trials. Conclusions: Relational communication with research doctors and nurses was significantly related to thoughts about remaining enrolled or dropping out of a clinical trial among adult participants in cancer treatment clinical trials. Practice Implications: Relational communication with cancer patients advances retention in research. © 2019, © 2019 Taylor & Francis Group, LLC.
Keywords: adult; aged; aged, 80 and over; middle aged; young adult; clinical trials as topic; neoplasm; neoplasms; psychology; questionnaire; communication; behavior; intention; interpersonal communication; cross-sectional study; cross-sectional studies; research subject; human relation; ethics; retention; clinical trial (topic); trust; research subjects; patient dropouts; very elderly; humans; human; male; female; cancer clinical trials; surveys and questionnaires; communication with research doctor; communication with research nurse; patient dropout; researcher-subject relations
Journal Title: AJOB Empirical Bioethics
Volume: 10
Issue: 3
ISSN: 2329-4515
Publisher: Taylor & Francis Group  
Date Published: 2019-01-01
Start Page: 190
End Page: 200
Language: English
DOI: 10.1080/23294515.2019.1618417
PUBMED: 31180295
PROVIDER: scopus
PMCID: PMC8653510
DOI/URL:
Notes: Article -- Export Date: 1 November 2022 -- Source: Scopus
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  1. Jun J Mao
    244 Mao