Advances in the treatment of pediatric solid tumors: A 50-year perspective Review


Authors: LaQuaglia, M. P.; Gerstle, J. T.
Review Title: Advances in the treatment of pediatric solid tumors: A 50-year perspective
Abstract: In the United States, more than 10 000 cancers occur annually in children aged 0–14 years, and more than 5000 in adolescents aged 15–19. In the last 50 years, significant advances have been made in imaging, molecular pathology, stage and risk assessment, surgical approach, multidisciplinary treatment, and survival for pediatric solid tumors (particularly neuroblastoma, Wilms tumor, rhabdomyosarcoma, and hepatoblastoma). Moreover, the molecular driver for fibrolamellar hepatocellular carcinoma, which occurs in adolescence and young adulthood, has been identified. © 2022 Wiley Periodicals LLC.
Keywords: adolescent; adult; cancer survival; child; cancer surgery; young adult; cancer risk; liver cell carcinoma; carcinoma, hepatocellular; united states; cancer staging; nuclear magnetic resonance imaging; cancer diagnosis; computer assisted tomography; surgical approach; ultrasound; risk assessment; neuroblastoma; echography; thorax radiography; rhabdomyosarcoma; nephroblastoma; history of medicine; desmoplastic small round cell tumor; cumulative incidence; molecular pathology; medical history; liver arteriography; wilms tumor; pediatric surgery; intravenous pyelography; hepatoblastoma; dsrct; humans; human; article; fibrolamellar hepatocellular carcinoma; multidisciplinary team; positron emission tomography-computed tomography; pediatric patient; pediatric liver tumors
Journal Title: Journal of Surgical Oncology
Volume: 126
Issue: 5
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2022-10-01
Start Page: 933
End Page: 942
Language: English
DOI: 10.1002/jso.27038
PUBMED: 36087080
PROVIDER: scopus
PMCID: PMC9473291
DOI/URL:
Notes: Article -- Export Date: 3 October 2022 -- Source: Scopus
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  1. Justin Theodore Gerstle
    24 Gerstle