Implementation of an evidence-based practice change removing heparin from implanted vascular access devices Journal Article


Authors: Hoffman, M.; Fischer-Cartlidge, E.
Article Title: Implementation of an evidence-based practice change removing heparin from implanted vascular access devices
Abstract: The objective of this article was to describe the implementation and outcomes of an evidence-based practice change to remove heparin from implanted vascular access device (IVAD) management. An extensive search of the literature was performed, and articles were appraised and synthesized to determine the best practice. A common theme emerged from the literature, showing that 0.9% sodium chloride alone can be as effective as heparin in preventing occlusion in IVADs. In this nurse-led initiative, heparin was successfully removed from the IVAD deaccess process and replaced with a 0.9% sodium chloride flush using a pulsatile flushing technique. Alteplase administration rates were used to measure success of the project, with no statistically significant change observed in alteplase rates 6 mo postimplementation. Successful implementation of this practice change demonstrates that 0.9% sodium chloride may be used for IVAD lock when deaccessing. Copyright © 2022 Infusion Nurses Society.
Keywords: evidence based practice; evidence-based practice; heparin; sodium chloride; tissue plasminogen activator; vascular access device; humans; human; vascular access devices
Journal Title: Journal of Infusion Nursing
Volume: 45
Issue: 5
ISSN: 1533-1458
Publisher: Lippincott Williams & Wilkins  
Date Published: 2022-09-01
Start Page: 258
End Page: 263
Language: English
DOI: 10.1097/nan.0000000000000482
PUBMED: 36112873
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 3 October 2022 -- Source: Scopus
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