Challenges with common laboratory tests in the adult cancer patient Book Section


Authors: McCash, S. I.; Pessin, M. S.
Editors: Ramanathan, L. V.; Fleisher, M.; Duffy, M. J.
Article/Chapter Title: Challenges with common laboratory tests in the adult cancer patient
Title Series: Clinical Aspects and Laboratory Determination
Abstract: Laboratory testing in cancer patients poses some unique challenges due to both the patient’s cancer as well as the treatments for the patient’s cancer. Cancers hijack the patient’s normal physiological processes such as cell growth, cell death, vessel growth, inflammation, and coagulation in ways that are generally abnormal; thus the laboratory measurements of such processes reflect these abnormalities. In addition, various cancer treatments, while killing off the cancer cells, can also have effects on the patient’s normal tissues which may be reflected in expected and unexpected abnormal laboratory measurements. In addition, some treatment methodologies directly interfere with the testing methods themselves. In this chapter, we describe a wide range of challenges to the performance and interpretation of common laboratory tests in the adult cancer patient. © 2022 Elsevier Inc. All rights reserved.
Keywords: oncology; cancer patients; laboratory medicine; biologic variation; laboratory test results
Book Title: Cancer Biomarkers: Clinical Aspects and Laboratory Determination
ISBN: 978-0-12-824302-2
Publisher: Elsevier Inc.  
Publication Place: Amsterdam, Netherlands
Date Published: 2022-01-01
Start Page: 67
End Page: 92
Language: English
DOI: 10.1016/b978-0-12-824302-2.00002-3
PROVIDER: scopus
DOI/URL:
Notes: Book Chapter: 3; This is the 5th volume in Clinical Aspects and Laboratory Determination -- Source: Scopus
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  1. Samuel Isaac McCash
    13 McCash