Sporadic medullary thyroid carcinoma Book Section
| Authors: | Roman, B. R.; Wong, R. J. |
| Editor: | Randolph, G. W. |
| Article/Chapter Title: | Sporadic medullary thyroid carcinoma |
| Abstract: | Sporadic medullary thyroid carcinoma (MTC) is a rare disorder with a variable clinical course. On average, MTC is more aggressive than differentiated thyroid cancer. This chapter reviews the pathophysiology, including genetics and the difference between sporadic and hereditary MTC; clinical presentation and usual clinical course; diagnostic considerations, including workup and staging; primary surgical treatment decision-making, follow-up and surveillance; surgical management of recurrent disease; radiation therapy; and management of distant metastatic disease, including systemic and targeted therapies. © 2021 Elsevier Inc. All rights reserved. |
| Keywords: | calcitonin; thyroidectomy; tyrosine kinase inhibitor (tki); sporadic medullary thyroid carcinoma (mtc) |
| Book Title: | Surgery of the Thyroid and Parathyroid Glands. 3rd ed |
| ISBN: | 978-0-323-66127-0 |
| Publisher: | Elsevier Inc. |
| Publication Place: | Philadelphia, PA |
| Date Published: | 2021-01-01 |
| Start Page: | 229 |
| End Page: | 234 |
| Language: | English |
| DOI: | 10.1016/b978-0-323-66127-0.00026-0 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 26 -- Located within "Section 4: Thyroid Neoplasia" -- Export Date: 3 October 2022 -- Source: Scopus |
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