Association of low and intermediate combined positive scores with outcomes of treatment with pembrolizumab in patients with recurrent and metastatic head and neck squamous cell carcinoma: Secondary analysis of keynote 048 Research Letter


Authors: Yu, Y.; Zakeri, K.; Sherman, E. J.; Lee, N. Y.
Title: Association of low and intermediate combined positive scores with outcomes of treatment with pembrolizumab in patients with recurrent and metastatic head and neck squamous cell carcinoma: Secondary analysis of keynote 048
Abstract: This secondary analysis of the Keynote 048 trial examines treatment with pembrolizumab in patients with recurrent and metastatic head and neck squamous cell carcinoma.
Keywords: confidence intervals; data analysis software; secondary analysis; descriptive statistics; treatment outcomes; neoplasm recurrence, local -- drug therapy; antibodies, monoclonal -- therapeutic use; cancer patients; neoplasm metastasis -- drug therapy; cox proportional hazards model; log-rank test; human; squamous cell carcinoma of head and neck -- drug therapy
Journal Title: JAMA Oncology
Volume: 8
Issue: 8
ISSN: 2374-2437
Publisher: American Medical Association  
Date Published: 2022-08-01
Start Page: 1216
End Page: 1218
Language: English
DOI: 10.1001/jamaoncol.2022.1846
PROVIDER: EBSCOhost
PROVIDER: cinahl
PMCID: PMC9185518
PUBMED: 35679031
DOI/URL:
Notes: Accession Number: 158627761 -- Entry Date: 20220830 -- Revision Date: 20220830 -- Publication Type: Article; letter; research; tables/charts -- Journal Subset: Peer Reviewed; USA. -- Source: Cinahl
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  1. Eric J Sherman
    344 Sherman
  2. Nancy Y. Lee
    880 Lee
  3. Yao Yu
    115 Yu
  4. Kaveh Zakeri
    83 Zakeri