Top ten tips palliative care clinicians should know about psychedelic-assisted therapy in the context of serious illness Review


Authors: Rosa, W. E.; Sager, Z.; Miller, M.; Bernstein, I.; Doerner Rinaldi, A.; Addicott, K.; Ljuslin, M.; Adrian, C.; Back, A. L.; Beachy, J.; Bossis, A. P.; Breitbart, W. S.; Cosimano, M. P.; Fischer, S. M.; Guss, J.; Knighton, E.; Phelps, J.; Richards, B. D.; Richards, W. A.; Tulsky, J. A.; Williams, M. T.; Beaussant, Y.
Review Title: Top ten tips palliative care clinicians should know about psychedelic-assisted therapy in the context of serious illness
Abstract: Psychedelic-assisted therapy (PAT) is a burgeoning treatment with growing interest across a variety of settings and disciplines. Empirical evidence supports PAT as a novel therapeutic approach that provides safe and effective treatment for people suffering from a variety of diagnoses, including treatment-resistant depression, substance use disorder, and post-traumatic stress disorder. Within the palliative care (PC) field, one-time PAT dosing may lead to sustained reductions in anxiety, depression, and demoralization - symptoms that diminish the quality of life in both seriously ill patients and those at end of life. Despite a well-noted psychedelic renaissance in scholarship and a renewed public interest in the utilization of these medicines, serious illness-specific content to guide PAT applications in hospice and PC clinical settings has been limited. This article offers 10 evidence-informed tips for PC clinicians synthesized through consultation with interdisciplinary and international leading experts in the field with aims to: (1) familiarize PC clinicians and teams with PAT; (2) identify the unique challenges pertaining to this intervention given the current legalities and logistical barriers; (3) discuss therapeutic competencies and considerations for current and future PAT use in PC; and (4) highlight critical approaches to optimize the safety and potential benefits of PAT among patients with serious illness and their caregivers. © Copyright 2022, Mary Ann Liebert, Inc.
Keywords: palliative care; quality of life; palliative therapy; depression; anxiety; palliative nursing; demoralization; serious illness; humans; human; hospice and palliative care nursing; psilocybin; hallucinogens; psychedelic-assisted therapy; psychedelics; mdma; anxiety treatment; lsd; psychedelic agent
Journal Title: Journal of Palliative Medicine
Volume: 25
Issue: 8
ISSN: 1096-6218
Publisher: Mary Ann Liebert, Inc  
Date Published: 2022-08-01
Start Page: 1273
End Page: 1281
Language: English
DOI: 10.1089/jpm.2022.0036
PUBMED: 35285721
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 September 2022 -- Source: Scopus
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  1. William S Breitbart
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  2. William   Rosa
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