What experts think about prostate cancer management during the COVID-19 pandemic: Report from the Advanced Prostate Cancer Consensus Conference 2021 Editorial


Authors: Turco, F.; Armstrong, A.; Attard, G.; Beer, T. M.; Beltran, H.; Bjartell, A.; Bossi, A.; Briganti, A.; Bristow, R. G.; Bulbul, M.; Caffo, O.; Chi, K. N.; Clarke, C.; Clarke, N.; Davis, I. D.; de Bono, J.; Duran, I.; Eeles, R.; Efstathiou, E.; Efstathiou, J.; Evans, C. P.; Fanti, S.; Feng, F. Y.; Fizazi, K.; Frydenberg, M.; George, D.; Gleave, M.; Halabi, S.; Heinrich, D.; Higano, C.; Hofman, M. S.; Hussain, M.; James, N.; Jones, R.; Kanesvaran, R.; Khauli, R. B.; Klotz, L.; Leibowitz, R.; Logothetis, C.; Maluf, F.; Millman, R.; Morgans, A. K.; Morris, M. J.; Mottet, N.; Mrabti, H.; Murphy, D. G.; Murthy, V.; Oh, W. K.; Onyeanunam, N. E.; Ost, P.; O'Sullivan, J. M.; Padhani, A. R.; Parker, C.; Poon, D. M. C.; Pritchard, C. C.; Rabah, D. M.; Rathkopf, D.; Reiter, R. E.; Rubin, M.; Ryan, C. J.; Saad, F.; Sade, J. P.; Sartor, O.; Scher, H. I.; Shore, N.; Skoneczna, I.; Small, E.; Smith, M.; Soule, H.; Spratt, D.; Sternberg, C. N.; Suzuki, H.; Sweeney, C.; Sydes, M.; Taplin, M. E.; Tilki, D.; Tombal, B.; Türkeri, L.; Uemura, H.; Uemura, H.; van Oort, I.; Yamoah, K.; Ye, D.; Zapatero, A.; Gillessen, S.; Omlin, A.
Title: What experts think about prostate cancer management during the COVID-19 pandemic: Report from the Advanced Prostate Cancer Consensus Conference 2021
Abstract: Patients with advanced prostate cancer (APC) may be at greater risk for severe illness, hospitalisation, or death from coronavirus disease 2019 (COVID-19) due to male gender, older age, potential immunosuppressive treatments, or comorbidities. Thus, the optimal management of APC patients during the COVID-19 pandemic is complex. In October 2021, during the Advanced Prostate Cancer Consensus Conference (APCCC) 2021, the 73 voting members of the panel members discussed and voted on 13 questions on this topic that could help clinicians make treatment choices during the pandemic. There was a consensus for full COVID-19 vaccination and booster injection in APC patients. Furthermore, the voting results indicate that the expert's treatment recommendations are influenced by the vaccination status: the COVID-19 pandemic altered management of APC patients for 70% of the panellists before the vaccination was available but only for 25% of panellists for fully vaccinated patients. Most experts (71%) were less likely to use docetaxel and abiraterone in unvaccinated patients with metastatic hormone-sensitive prostate cancer. For fully vaccinated patients with high-risk localised prostate cancer, there was a consensus (77%) to follow the usual treatment schedule, whereas in unvaccinated patients, 55% of the panel members voted for deferring radiation therapy. Finally, there was a strong consensus for the use of telemedicine for monitoring APC patients. Patient summary: In the Advanced Prostate Cancer Consensus Conference 2021, the panellists reached a consensus regarding the recommendation of the COVID-19 vaccine in prostate cancer patients and use of telemedicine for monitoring these patients. © 2022 The Authors
Keywords: cancer chemotherapy; advanced cancer; conference paper; pathology; cancer therapy; docetaxel; prostate cancer; prostatic neoplasms; prostate tumor; vaccination; androgen antagonists; consensus development; alternative medicine; antiandrogen; androgen deprivation therapy; abiraterone; telemedicine; pandemic; cabazitaxel; enzalutamide; humans; human; male; metastatic castration resistant prostate cancer; apalutamide; pandemics; coronavirus disease 2019; covid-19; covid-19 pandemic; covid-19 vaccines; sars-cov-2 vaccine; covid-19 boost injection; covid-19 vaccine; prostate cancer management; vaccinee
Journal Title: European Urology
Volume: 82
Issue: 1
ISSN: 0302-2838
Publisher: Elsevier Science, Inc.  
Date Published: 2022-07-01
Start Page: 6
End Page: 11
Language: English
DOI: 10.1016/j.eururo.2022.02.010
PUBMED: 35393158
PROVIDER: scopus
PMCID: PMC8849852
DOI/URL:
Notes: Erratum issued, see DOI: 10.1016/j.eururo.2022.04.004 -- Source: Scopus
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  1. Michael Morris
    578 Morris
  2. Dana Elizabeth Rathkopf
    273 Rathkopf
  3. Howard Scher
    1130 Scher