Disparities in timely treatment among young women with breast cancer Journal Article
| Authors: | Jain, U.; Jain, B.; Fayanju, O. M.; Chino, F.; Dee, E. C. |
| Article Title: | Disparities in timely treatment among young women with breast cancer |
| Abstract: | Background: Although evidence suggests worse breast cancer-specific survival associated with treatment delay beyond 90 days, little is known regarding the sociodemographic predictors of delays in cancer-directed surgery among young women with breast cancer. This is particularly notable, given that 5–10% of new diagnoses occur in younger women aged <40 years, commonly with more aggressive features than in older women. Methods: We used the National Cancer Database (2004–2017) to assess sociodemographic disparities in delay of upfront surgery beyond 90 days among young women with non-metastatic breast cancer, using multivariable logistic regression and predictive marginal modeling. Results: Black women experienced treatment delays more frequently than white women (aOR: 1.93 [95% CI: 1.76–2.11], p < 0.001). Adjusted rates of treatment delay were 4.91% [95% CI: 4.51%–5.30%] and 2.60% [95% CI: 2.47%–2.74%] for Black and white women, respectively, and 2.97% [95% CI: 2.83%–3.12%], 2.36% [95% CI: 2.03%–2.68%], and 1.18% [95% CI: 0.54%–1.81%] for women from metro, urban, and rural areas, respectively. Conclusion: These results suggest that improving access to timely treatment may be leveraged as a means through which to lessen the breast cancer disparities experienced by Black women. © 2022 Elsevier Inc. |
| Keywords: | adult; controlled study; major clinical study; cancer patient; breast cancer; odds ratio; data base; confidence interval; therapy delay; surgery; age distribution; logistic regression analysis; racial disparity; breast surgery; caucasian; health care disparity; women's health; racial disparities; urban area; rural area; time to treatment; predictive model; human; female; article; black person; sociodemographics; cancer disparities; treatment delay; aya; rural health; social inequality; adolescents and young adults with cancer; rural health disparities; adolescent and young adult with cancer |
| Journal Title: | American Journal of Surgery |
| Volume: | 224 |
| Issue: | 2 |
| ISSN: | 0002-9610 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2022-08-01 |
| Start Page: | 811 |
| End Page: | 815 |
| Language: | English |
| DOI: | 10.1016/j.amjsurg.2022.01.019 |
| PUBMED: | 35090684 |
| PROVIDER: | scopus |
| PMCID: | PMC9304449 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 August 2022 -- Source: Scopus |
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