Activity of AZD7442 (tixagevimab-cilgavimab) against Omicron SARS-CoV-2 in patients with hematologic malignancies Research Letter


Authors: Stuver, R.; Shah, G. L.; Korde, N. S.; Roeker, L. E.; Mato, A. R.; Batlevi, C. L.; Chung, D. J.; Doddi, S.; Falchi, L.; Gyurkocza, B.; Hamilton, A.; Lin, Y. H.; Jakubowski, A. A.; Joffe, E.; Landau, H. L.; Lin, R. J.; Mailankody, S.; Palomba, M. L.; Park, J. H.; Perales, M. A.; Ponce, D. M.; Ramanathan, L. V.; Salles, G. A.; Scordo, M.; Seo, S. K.; Shah, U. A.; Stein, E. M.; Straus, D.; Usmani, S. Z.; Young, J. W.; Zelenetz, A. D.; Noy, A.; Vardhana, S. A.
Title: Activity of AZD7442 (tixagevimab-cilgavimab) against Omicron SARS-CoV-2 in patients with hematologic malignancies
Keywords: adult; major clinical study; drug activity; drug efficacy; nonhuman; follow up; letter; wild type; monoclonal antibody; antibodies, monoclonal; hematologic malignancy; nonhodgkin lymphoma; hematologic neoplasms; drug combination; single drug dose; drug combinations; observational study; immunoglobulin g antibody; receptor binding; hematologic disease; antibody titer; randomized controlled trial (topic); virus mutation; neutralizing antibody; antibodies, neutralizing; virus neutralization; severe acute respiratory syndrome; pre-exposure prophylaxis; humans; human; virus spike protein; chimeric antigen receptor t-cell immunotherapy; severe acute respiratory syndrome coronavirus 2; coronavirus disease 2019; covid-19; sars-cov-2; cilgavimab plus tixagevimab; sotrovimab; cilgavimab; cilgavimab and tixagevimab drug combination; tixagevimab; patient history of stem cell transplantation; sars-cov-2 omicron; surrogate virus neutralization test
Journal Title: Cancer Cell
Volume: 40
Issue: 6
ISSN: 1535-6108
Publisher: Cell Press  
Date Published: 2022-06-13
Start Page: 590
End Page: 591
Language: English
DOI: 10.1016/j.ccell.2022.05.007
PUBMED: 35598602
PROVIDER: scopus
PMCID: PMC9108069
DOI/URL:
Notes: The PDF includes a typo in Heather Landau's name; The author's middle initial is formatted as: Heather L. Landau, the correct middle initial is: Heather J. Landau -- Source: Scopus
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MSK Authors
  1. Emily Margaret Stein
    5 Stein
  2. Ariela Noy
    369 Noy
  3. Susan Seo
    122 Seo
  4. Maria Lia Palomba
    442 Palomba
  5. Jae Hong Park
    374 Park
  6. Andrew D Zelenetz
    781 Zelenetz
  7. Doris Ponce
    257 Ponce
  8. Miguel-Angel Perales
    940 Perales
  9. Heather Jolie Landau
    432 Landau
  10. James W Young
    319 Young
  11. David J Straus
    360 Straus
  12. David Chung
    249 Chung
  13. Michael Scordo
    383 Scordo
  14. Connie Wing-Ching Lee Batlevi
    177 Batlevi
  15. Boglarka   Gyurkocza
    138 Gyurkocza
  16. Neha Sanat Korde
    235 Korde
  17. Gunjan Lalitchandra Shah
    441 Shah
  18. Santosha Adipudi Vardhana
    112 Vardhana
  19. Erel Joffe
    84 Joffe
  20. Richard Jirui Lin
    130 Lin
  21. Anthony R Mato
    236 Mato
  22. Lindsey Elizabeth Roeker
    142 Roeker
  23. Urvi A Shah
    198 Shah
  24. Sital Doddi
    10 Doddi
  25. Lorenzo Falchi
    131 Falchi
  26. Gilles Andre Salles
    303 Salles
  27. Robert Nicolais Stuver
    73 Stuver
  28. Saad Zafar Usmani
    327 Usmani
  29. Ya-Hui Lin
    9 Lin