Activity of AZD7442 (tixagevimab-cilgavimab) against Omicron SARS-CoV-2 in patients with hematologic malignancies Research Letter


Authors: Stuver, R.; Shah, G. L.; Korde, N. S.; Roeker, L. E.; Mato, A. R.; Batlevi, C. L.; Chung, D. J.; Doddi, S.; Falchi, L.; Gyurkocza, B.; Hamilton, A.; Lin, Y. H.; Jakubowski, A. A.; Joffe, E.; Landau, H. L.; Lin, R. J.; Mailankody, S.; Palomba, M. L.; Park, J. H.; Perales, M. A.; Ponce, D. M.; Ramanathan, L. V.; Salles, G. A.; Scordo, M.; Seo, S. K.; Shah, U. A.; Stein, E. M.; Straus, D.; Usmani, S. Z.; Young, J. W.; Zelenetz, A. D.; Noy, A.; Vardhana, S. A.
Title: Activity of AZD7442 (tixagevimab-cilgavimab) against Omicron SARS-CoV-2 in patients with hematologic malignancies
Keywords: adult; major clinical study; drug activity; drug efficacy; nonhuman; follow up; letter; wild type; monoclonal antibody; antibodies, monoclonal; hematologic malignancy; nonhodgkin lymphoma; hematologic neoplasms; drug combination; single drug dose; drug combinations; observational study; immunoglobulin g antibody; receptor binding; hematologic disease; antibody titer; randomized controlled trial (topic); virus mutation; neutralizing antibody; antibodies, neutralizing; virus neutralization; severe acute respiratory syndrome; pre-exposure prophylaxis; humans; human; virus spike protein; chimeric antigen receptor t-cell immunotherapy; severe acute respiratory syndrome coronavirus 2; coronavirus disease 2019; covid-19; sars-cov-2; cilgavimab plus tixagevimab; sotrovimab; cilgavimab; cilgavimab and tixagevimab drug combination; tixagevimab; patient history of stem cell transplantation; sars-cov-2 omicron; surrogate virus neutralization test
Journal Title: Cancer Cell
Volume: 40
Issue: 6
ISSN: 1535-6108
Publisher: Cell Press  
Date Published: 2022-06-13
Start Page: 590
End Page: 591
Language: English
DOI: 10.1016/j.ccell.2022.05.007
PUBMED: 35598602
PROVIDER: scopus
PMCID: PMC9108069
DOI/URL:
Notes: The PDF includes a typo in Heather Landau's name; The author's middle initial is formatted as: Heather L. Landau, the correct middle initial is: Heather J. Landau -- Source: Scopus
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MSK Authors
  1. Emily Margaret Stein
    5 Stein
  2. Ariela Noy
    351 Noy
  3. Susan Seo
    120 Seo
  4. Maria Lia Palomba
    415 Palomba
  5. Jae Hong Park
    356 Park
  6. Andrew D Zelenetz
    767 Zelenetz
  7. Doris Ponce
    254 Ponce
  8. Miguel-Angel Perales
    913 Perales
  9. Heather Jolie Landau
    419 Landau
  10. James W Young
    318 Young
  11. David J Straus
    356 Straus
  12. David Chung
    240 Chung
  13. Michael Scordo
    365 Scordo
  14. Connie Wing-Ching Lee Batlevi
    176 Batlevi
  15. Boglarka   Gyurkocza
    134 Gyurkocza
  16. Neha Sanat Korde
    226 Korde
  17. Gunjan Lalitchandra Shah
    418 Shah
  18. Santosha Adipudi Vardhana
    102 Vardhana
  19. Erel Joffe
    82 Joffe
  20. Richard Jirui Lin
    124 Lin
  21. Anthony R Mato
    235 Mato
  22. Lindsey Elizabeth Roeker
    132 Roeker
  23. Urvi A Shah
    187 Shah
  24. Sital Doddi
    10 Doddi
  25. Lorenzo Falchi
    107 Falchi
  26. Gilles Andre Salles
    269 Salles
  27. Robert Nicolais Stuver
    57 Stuver
  28. Saad Zafar Usmani
    296 Usmani
  29. Ya-Hui Lin
    9 Lin