A community approach to the cancer-variant-interpretation bottleneck Editorial
| Authors: | Krysiak, K.; Danos, A. M.; Kiwala, S.; McMichael, J. F.; Coffman, A. C.; Barnell, E. K.; Sheta, L.; Saliba, J.; Grisdale, C. J.; Kujan, L.; Pema, S.; Lever, J.; Spies, N. C.; Chiorean, A.; Rieke, D. T.; Clark, K. A.; Jani, P.; Takahashi, H.; Horak, P.; Ritter, D. I.; Zhou, X.; Ainscough, B. J.; Delong, S.; Lamping, M.; Marr, A. R.; Li, B. V.; Lin, W. H.; Terraf, P.; Salama, Y.; Campbell, K. M.; Farncombe, K. M.; Ji, J.; Zhao, X.; Xu, X.; Kanagal-Shamanna, R.; Cotto, K. C.; Skidmore, Z. L.; Walker, J. R.; Zhang, J.; Milosavljevic, A.; Patel, R. Y.; Giles, R. H.; Kim, R. H.; Schriml, L. M.; Mardis, E. R.; Jones, S. J. M.; Raca, G.; Rao, S.; Madhavan, S.; Wagner, A. H.; Griffith, O. L.; Griffith, M. |
| Title: | A community approach to the cancer-variant-interpretation bottleneck |
| Keywords: | unclassified drug; somatic mutation; note; comparative study; neoplasm; neoplasms; gene; classification; genetic variability; genetic variation; evidence based practice; evolution; practice guideline; renal cell carcinoma; health service; tumor suppressor gene; fibrosarcoma; microsatellite instability; medical research; brain derived neurotrophic factor; carcinogenicity; feedback system; pathogenicity; von hippel lindau disease; decision making; genetic predisposition; community care; knowledge; transcription factor etv6; copy number variation; phase 1 clinical trial (topic); responsibility; cancer genome atlas; workflow; american society of clinical oncology; humans; human; whole exome sequencing; gene editing; precision oncology; malignant neoplasm; larotrectinib; application programming interface; ntrk gene; international cancer genome consortium; association for molecular pathology; interpretation bias; tyrosine receptor kinase 1; tyrosine receptor kinase 2; tyrosine receptor kinase 3; bottleneck population; cancer variant; clingen somatic cancer variant curation expert panels; clinical interpretation of variants in cancer; genome mining; germ line gene therapy; medical genomics japan variant database; network data exchange |
| Journal Title: | Nature Cancer |
| Volume: | 3 |
| Issue: | 5 |
| ISSN: | 2662-1347 |
| Publisher: | Nature Research |
| Date Published: | 2022-05-01 |
| Start Page: | 522 |
| End Page: | 525 |
| Language: | English |
| DOI: | 10.1038/s43018-022-00379-w |
| PUBMED: | 35624339 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Note -- Export Date: 1 July 2022 -- Source: Scopus |
