Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, Part II: Principles of active surveillance, principles of surgery, and follow-up Guidelines


Authors: Eastham, J. A.; Auffenberg, G. B.; Barocas, D. A.; Chou, R.; Crispino, T.; Davis, J. W.; Eggener, S.; Horwitz, E. M.; Kane, C. J.; Kirkby, E.; Lin, D. W.; McBride, S. M.; Morgans, A. K.; Pierorazio, P. M.; Rodrigues, G.; Wong, W. W.; Boorjian, S. A.
Title: Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, Part II: Principles of active surveillance, principles of surgery, and follow-up
Abstract: Purpose:The summary presented herein represents Part II of the three-part series dedicated to Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, discussing principles of active surveillance and surgery as well as follow-up for patients after primary treatment. Please refer to Parts I and III for discussion of risk assessment, staging, and risk-based management (Part I), and principles of radiation and future directions (Part III).Materials and Methods:The systematic review utilized to inform this guideline was conducted by an independent methodological consultant. A research librarian conducted searches in Ovid MEDLINE, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews. The methodology team supplemented searches of electronic databases with the studies included in the prior AUA review and by reviewing reference lists of relevant articles.Results:The Clinically Localized Prostate Cancer Panel created evidence- and consensus-based guideline statements to aid clinicians in the management of patients with clinically localized prostate cancer. Statements regarding active surveillance, surgical management, and patient follow-up are detailed.Conclusion:This guideline aims to inform clinicians treating patients with clinically localized prostate cancer. Continued research and publication of high-quality evidence from future trials will be essential to further improve care for these men. © 2022 Lippincott Williams and Wilkins. All rights reserved.
Keywords: follow up; follow-up studies; consensus; prostate cancer; prostatic neoplasms; active surveillance; watchful waiting; prostate tumor; radical prostatectomy; shared decision making; humans; human; male; systematic reviews as topic; radiation therapy for prostate cancer
Journal Title: Journal of Urology
Volume: 208
Issue: 1
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 2022-07-01
Start Page: 19
End Page: 25
Language: English
DOI: 10.1097/ju.0000000000002758
PUBMED: 35536148
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 July 2022 -- Source: Scopus
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MSK Authors
  1. James Eastham
    525 Eastham
  2. Sean Matthew McBride
    263 McBride