One committee to review it all: A single, multi-disciplinary COVID-19 Research Committee Journal Article
| Authors: | Migliacci, J.; Rodavitch, A.; Riely, G.; Sabbatini, P.; Houston, C.; Hanley, S. |
| Article Title: | One committee to review it all: A single, multi-disciplinary COVID-19 Research Committee |
| Abstract: | On 1/20/2020 when the first case of a novel coronavirus (COVID-19) was confirmed in Washington state, its major impact was unknown. Memorial Sloan Kettering Cancer Center's (MSK) Hospital Incident Command System (HICS) was activated on 2/5, with our first COVID-19 case identified in early March. By 3/17, our Protocol Activation and Human Research Protection Program was fully remote and on 3/23, MSK leadership requested the creation of the COVID-19 Research Committee. Given the race to identify safe and effective treatments for COVID-19, modifications to workflows and review processes were needed. The goal was to provide quick access to COVID-19 treatments to our patients by creating a COVID-19 Committee as a “one-stop” committee, providing comprehensive review of clinical research related to COVID-19 including scientific review mandated by the Cancer Center Support Grant (CCSG) guidelines, prior to IRB review and protocol activation. Protocols that were reviewed by the COVID-19 Committee opened to accrual in an unprecedented 44 days from submission to the committee to open to accrual. Patients were accrued on most of the therapeutic protocols within 1 day of opening. These statistics have prompted our institution to explore how more protocols can benefit from this “one-stop” committee structure. © 2022 Elsevier Inc. |
| Keywords: | covid-19; cancer center support grant (ccsg); protocol activation; protocol review committee; study start-up |
| Journal Title: | Contemporary Clinical Trials |
| Volume: | 117 |
| ISSN: | 1551-7144 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2022-06-01 |
| Start Page: | 106760 |
| Language: | English |
| DOI: | 10.1016/j.cct.2022.106760 |
| PUBMED: | 35460914 |
| PROVIDER: | scopus |
| PMCID: | PMC9020641 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 June 2022 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work