Cerebral toxoplasmosis in a patient with multiple myeloma Miscellaneous
| Authors: | Parasram, M.; Arevalo-Perez, J. |
| Title: | Cerebral toxoplasmosis in a patient with multiple myeloma |
| Abstract: | Background: Cerebral toxoplasmosis is a rare complication of relapsed/refractory multiple myeloma (MM) after autologous stem cell transplant (SCT). Imaging characteristics can be helpful in leading to rapid diagnosis and treatment. Case Description: A 76-year-old man with relapsed/refractory IgA kappa MM status post autologous SCT who presented to the hospital with altered mental status. His hospital course was complicated by rapid decompensation to obtundation requiring intubation. Magnetic resonance imaging (MRI) of the brain revealed numerous ringenhancing lesions with eccentric target signs, which were concerning for cerebral toxoplasmosis. Diagnosis was confirmed with positive toxoplasma cerebrospinal fluid polymerase chain reaction test. Conclusion: Cerebral toxoplasmosis should be considered in the differential diagnosis for MM patients who present with altered mental status and neurologic findings. The ring-enhancing lesion with eccentric target sign on MRI can be helpful in the diagnosis of cerebral toxoplasmosis. © 2022 Published by Scientific Scholar on behalf of Surgical Neurology International. |
| Keywords: | neuroimaging; multiple myeloma; cerebral toxoplasmosis; eccentric target sign; neuroinfectious disease |
| Journal Title: | Surgical Neurology International |
| Volume: | 13 |
| ISSN: | 2152-7806 |
| Publisher: | Scientific Scholar On Behalf of Surgical Neurology International |
| Date Published: | 2022-05-06 |
| Start Page: | 191 |
| Language: | English |
| DOI: | 10.25259/sni_271_2022 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 June 2022 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
Related MSK Work