Vive la résistance: T-cell immunity in the protection against SARS-CoV-2 infection Editorial
| Authors: | McGary, L. H. F.; Vardhana, S. A. |
| Title: | Vive la résistance: T-cell immunity in the protection against SARS-CoV-2 infection |
| Abstract: | Summary: Fahrner and colleagues investigated the immune response of patients with cancer and cancer-free individuals to SARS-CoV-2 and found that a propensity toward an IL5-predominant Th2/Tc2 response was predictive of susceptibility to infection. The results of this study also suggest that a cellular response against the Spike 1 protein receptor binding domain (S1-RBD) region of the SARS-CoV-2 proteome contributes to protection and that mutations in this region may drive viral evolution and immune escape. © 2022 American Association for Cancer Research. |
| Keywords: | genetics; t lymphocyte; t-lymphocytes; metabolism; immunology; membrane glycoproteins; membrane protein; viral envelope proteins; virus envelope protein; humans; human; covid-19; sars-cov-2; coronavirus spike glycoprotein; spike protein, sars-cov-2; spike glycoprotein, coronavirus |
| Journal Title: | Cancer Discovery |
| Volume: | 12 |
| Issue: | 4 |
| ISSN: | 2159-8274 |
| Publisher: | American Association for Cancer Research |
| Date Published: | 2022-04-01 |
| Start Page: | 892 |
| End Page: | 894 |
| Language: | English |
| DOI: | 10.1158/2159-8290.Cd-22-0080 |
| PUBMED: | 35373282 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 2 May 2022 -- Source: Scopus |
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