Triple-negative breast carcinomas of low malignant potential: Review on diagnostic criteria and differential diagnoses Review


Authors: Cima, L.; Kaya, H.; Marchiò, C.; Nishimura, R.; Wen, H. Y.; Fabbri, V. P.; Foschini, M. P.
Review Title: Triple-negative breast carcinomas of low malignant potential: Review on diagnostic criteria and differential diagnoses
Abstract: Triple-negative breast carcinomas constitute a wide spectrum of lesions, mostly being highly aggressive. Nevertheless, some special histologic subtypes can have low malignant potential. The purpose of the present paper is to review diagnostic criteria and prognostic parameters of breast neoplasms of special histotypes. Specifically, adenoid cystic carcinoma, adenomyoepithelioma, acinic cell carcinoma, mucoepidermoid carcinoma, tall cell carcinoma with reverse polarity, and secretory carcinoma will be discussed. For each tumour, definition and morphological and molecular features, together with prognostic parameters, will be presented. Paradigmatic cases will be illustrated. © 2021, The Author(s).
Keywords: diagnosis, differential; differential diagnosis; pathology; breast neoplasms; breast tumor; salivary gland tumor; salivary gland neoplasms; adenoid cystic carcinoma; acinar cell carcinoma; carcinoma, acinar cell; carcinoma, adenoid cystic; acinic cell carcinoma; triple negative breast cancer; mucoepidermoid carcinoma; adenomyoepithelioma; secretory carcinoma; humans; human; female; triple negative breast neoplasms; tall cell carcinoma with reverse polarity; triple-negative breast carcinoma
Journal Title: Virchows Archiv
Volume: 480
Issue: 1
ISSN: 0945-6317
Publisher: Springer  
Date Published: 2022-01-01
Start Page: 109
End Page: 126
Language: English
DOI: 10.1007/s00428-021-03174-7
PUBMED: 34458945
PROVIDER: scopus
PMCID: PMC8983547
DOI/URL:
Notes: Review -- Export Date: 25 April 2022 -- Source: Scopus
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  1. Hannah Yong Wen
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