Predictors of acute transfer and mortality within 6 months from admission to an inpatient rehabilitation facility for patients with brain tumors Journal Article


Authors: Knowlton, S. E.; Gundersen, A. I.; Reilly, J. M.; Tan, C. O.; Schneider, J. C.; Shih, S. L.
Article Title: Predictors of acute transfer and mortality within 6 months from admission to an inpatient rehabilitation facility for patients with brain tumors
Abstract: Objective: To obtain useful information for clinicians in evaluating patients with brain tumors for transfer to and subsequent care in inpatient rehabilitation facilities (IRFs). Design: Retrospective chart review. Setting: Inpatient rehabilitation facility. Participants: A total of 208 adults with either initial or recurrent brain tumors who were admitted to an IRF between January 2017 and December 2018 after an acute hospitalization. Interventions: None Main Outcome Measures: Transfer from an IRF to an acute care hospital and mortality within 6 months from admission to an IRF. Results: Of the 208 patients who met inclusion criteria, 20.2% were transferred to an acute care hospital during the IRF stay, which was associated with prior chemotherapy, steroid use, and laterality of tumor. In total, 36.9% of patients with brain tumors died within 6 months of an IRF admission that was associated with recurrent tumor diagnosis, prior chemotherapy, prior neurosurgical intervention, prior neurostimulant use, use of steroids, isocitrate dehydrogenase and O6-methyl-guanyl-methyl-transferase biomarkers, and laterality and location of tumor. Conclusions: Patients with brain tumors have a notable potential for acute hospital transfer and mortality within 6 months of IRF stay, with several tumor- and treatment-related risk factors. This information can help identify functional goals, identify high risk patients, enable closer clinical monitoring, and facilitate focused care discussions at IRFs. © 2021 The American Congress of Rehabilitation Medicine
Keywords: brain neoplasms; rehabilitation; inpatients
Journal Title: Archives of Physical Medicine and Rehabilitation
Volume: 103
Issue: 3
ISSN: 0003-9993
Publisher: W.B. Saunders Co.  
Date Published: 2022-03-01
Start Page: 424
End Page: 429
Language: English
DOI: 10.1016/j.apmr.2021.10.019
PUBMED: 34762854
PROVIDER: scopus
PMCID: PMC9446107
DOI/URL:
Notes: Article -- Export Date: 1 March 2022 -- Source: Scopus
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  1. Julia M Reilly
    5 Reilly